A Comprehensive Review on Molecular Mechanisms, Treatments, and Brief Role of Natural Products in Hepatocellular Cancer

IF 1.5 4区医学 Q4 CHEMISTRY, MEDICINAL

Natural Product Communications Pub Date : 2024-09-01 DOI:10.1177/1934578x241284873

Linlin Jiang, Qin Meng, Lixiu Liu, Weihang Li

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引用次数: 1

Abstract

Most initial liver cancers are hepatocellular carcinomas (HCC), which make up the vast majority of cases. Hepatitis B or C virus infection as well as alcohol consumption is among the key risk factors. The significance of the most intriguing soluble factors as indicators for early diagnosis and as suggested targets for therapy in light of the increasing challenges in precision medicine. The development of HCC is influenced by a complex combination between pro-inflammatory and anti-inflammatory cytokines and their signalling cascades. Recently,researchers are aims to assess the potential of a number of distinct molecular cascade/cascade including cytokines to function as key players with particular underlying etiologies. Increasing our knowledge of the signaling network that links retro differentiation and inflammationmay help us find novel therapeutic targets and develop combined therapies or treatments that work against tumors with a significant degree of heterogeneity. With nursing processes at its center, comprehensive nursing care is a new nursing paradigm that combines the benefits of primary and group nursin g as well as a perfect synthesis of many nursing metrics like nursing philosophy, nursing plan, and nursing quality evaluation. In order to treat patients with serious liver diseases like cancer, it can conduct nursing interventions item by item in accordance with the unique disease conditions of each patient and combine efficient therapeutic approaches with high-quality nursing modes. Dietary natural products, including fruits, vegetables, and spices, may prevent and treat liver cancer by inhibiting tumor growth, protecting the liver, and enhancing chemotherapy.

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天然产物在肝细胞癌中的分子机制、治疗和作用综述

大多数原发性肝癌是肝细胞癌（HCC），占绝大多数病例。乙型或丙型肝炎病毒感染以及饮酒是主要的危险因素。最有趣的可溶性因子作为早期诊断指标的重要性，以及在精准医学日益增长的挑战下作为建议的治疗目标。HCC的发展受到促炎和抗炎细胞因子及其信号级联反应的复杂组合的影响。最近，研究人员的目标是评估一系列不同的分子级联/级联，包括细胞因子，在特定的潜在病因中发挥关键作用的潜力。增加我们对连接复古分化和炎症的信号网络的了解，可能有助于我们找到新的治疗靶点，并开发出针对具有显著异质性的肿瘤的联合疗法或治疗方法。综合护理是一种新的护理模式，以护理过程为中心，结合了初级护理和团体护理的优点，并将许多护理指标如护理哲学、护理计划和护理质量评估完美地综合在一起。针对癌症等严重肝病患者，可根据每位患者独特的疾病情况，逐项进行护理干预，将高效的治疗手段与优质的护理模式相结合。饮食中的天然产品，包括水果、蔬菜和香料，可以通过抑制肿瘤生长、保护肝脏和加强化疗来预防和治疗肝癌。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Natural Product Communications 工程技术-食品科技

CiteScore

3.10

自引率

11.10%

发文量

254

审稿时长

2.7 months

期刊介绍： Natural Product Communications is a peer reviewed, open access journal studying all aspects of natural products, including isolation, characterization, spectroscopic properties, biological activities, synthesis, structure-activity, biotransformation, biosynthesis, tissue culture and fermentation. It covers the full breadth of chemistry, biochemistry, biotechnology, pharmacology, and chemical ecology of natural products. Natural Product Communications is a peer reviewed, open access journal studying all aspects of natural products, including isolation, characterization, spectroscopic properties, biological activities, synthesis, structure-activity, biotransformation, biosynthesis, tissue culture and fermentation. It covers the full breadth of chemistry, biochemistry, biotechnology, pharmacology, and chemical ecology of natural products. Natural Product Communications is a peer reviewed, open access journal studying all aspects of natural products, including isolation, characterization, spectroscopic properties, biological activities, synthesis, structure-activity, biotransformation, biosynthesis, tissue culture and fermentation. It covers the full breadth of chemistry, biochemistry, biotechnology, pharmacology, and chemical ecology of natural products.