Calculation of silent substitution stimuli for full-field electroretinography using the SilentSubstiTutor application.

IF 2 4区医学 Q2 OPHTHALMOLOGY

Documenta Ophthalmologica Pub Date : 2026-04-01 Epub Date: 2026-03-14 DOI:10.1007/s10633-026-10090-1

Cord Huchzermeyer, Jan Kremers

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引用次数: 0

Abstract

Purpose: The silent substitution technique allows photoreceptor directed stimulation (i.e., the selective stimulation of different photoreceptor types or a specific combination of photoreceptor types).

Methods: Calculation of these stimuli is not trivial, requiring complex matrix calculations based on specific datasets (spectral power distributions of primary lights, photoreceptor fundamentals, and optical densities of pre-receptoral filters). Several tools have been published that facilitate these calculations, including an excel file and a python library, but these are difficult to use without prior knowledge.

Results: We introduce an online application that allows calculation of silent substitution stimuli in a graphical user interface (GUI) for common use-cases (3 to 5 primary lights, periodic stimuli modulated around an average setting of the test field, 10° standard observers).

Conclusion: The goal is to provide a practical tool that can be used in these cases, but that can also be used as a teaching tool for beginners who plan to use the more sophisticated methods.

查看原文本刊更多论文

使用SilentSubstiTutor应用程序计算全场视网膜电图的无声替代刺激。

目的：无声替代技术允许光感受器定向刺激（即不同光感受器类型或特定光感受器类型组合的选择性刺激）。方法：这些刺激的计算并不简单，需要基于特定数据集（主光源的光谱功率分布、光感受器基本原理和前感受器滤光器的光密度）进行复杂的矩阵计算。已经发布了一些工具来促进这些计算，包括一个excel文件和一个python库，但是如果没有事先的知识，这些工具很难使用。结果：我们引入了一个在线应用程序，该应用程序允许在图形用户界面（GUI）中为常见用例（3至5个主光源，围绕测试场的平均设置调制的周期性刺激，10°标准观察者）计算无声替代刺激。结论：目的是提供一个实用的工具，可以在这些情况下使用，但也可以作为一个教学工具，初学者谁计划使用更复杂的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Documenta Ophthalmologica 医学-眼科学

CiteScore

3.50

自引率

21.40%

发文量

审稿时长

>12 weeks

期刊介绍： Documenta Ophthalmologica is an official publication of the International Society for Clinical Electrophysiology of Vision. The purpose of the journal is to promote the understanding and application of clinical electrophysiology of vision. Documenta Ophthalmologica will publish reviews, research articles, technical notes, brief reports and case studies which inform the readers about basic and clinical sciences related to visual electrodiagnosis and means to improve diagnosis and clinical management of patients using visual electrophysiology. Studies may involve animals or humans. In either case appropriate care must be taken to follow the Declaration of Helsinki for human subject or appropriate humane standards of animal care (e.g., the ARVO standards on Animal Care and Use).