Assessment of changes in late positive potential during emotion regulation: Evidence from a three-level meta-analysis

IF 3.7 3区医学 Q2 NEUROSCIENCES

Brain Research Bulletin Pub Date : 2026-01-01 Epub Date: 2025-12-20 DOI:10.1016/j.brainresbull.2025.111700

Xuejing Zou, Han Xiao, Siyu Di, Haiying Qu

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引用次数: 0

Abstract

Objective

A growing body of research has employed event-related potential (ERP) techniques to investigate emotion regulation. However, studies utilizing consistent indicators have yielded divergent and at times contradictory findings. The primary objectives of this study are to systematically evaluate whether significant changes occur in the amplitude of the late positive potential (LPP), a key ERP component, during emotion regulation, and to further assess the temporal dynamics of LPP modulation across different processing stages.

Methods

A total of three databases—PubMed, Web of Science, and PsycINFO—were searched for electroencephalography studies related to emotion regulation published between the year 2000 and March 1, 2025, resulting in the inclusion of 48 studies with 150 effect sizes. This meta-analysis utilized CMA3.0 and R4.5 software. When a study reported multiple effect sizes, a three-level meta-analysis was conducted, and publication bias was assessed using funnel plots, the Egger test at the two- and three-levels.

Results

The results indicated significant total effect sizes in the central-parietal region across the full, early, and late time windows, while total effect sizes in other brain regions and time windows did not reach statistical significance.

Conclusions

The LPP in the central parietal serves as a reliable electrophysiological indicator of emotion regulation (especially cognitive reappraisal), and differences induced by this emotion regulation are more pronounced in early and late time windows.

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情绪调节过程中后期正电位变化的评估：来自三水平荟萃分析的证据。

目的：越来越多的研究采用事件相关电位（ERP）技术来研究情绪调节。然而，使用一致指标的研究产生了分歧，有时甚至是相互矛盾的结果。本研究的主要目的是系统地评估情绪调节过程中后期正电位（LPP）的振幅是否发生显著变化，并进一步评估LPP调制在不同加工阶段的时间动态。方法：共检索pubmed、Web of Science和psycininfo三个数据库，检索2000年至2025年3月1日期间发表的与情绪调节相关的脑电图研究，结果纳入48项研究，150个效应量。本meta分析采用CMA3.0和R4.5软件。当一项研究报告了多个效应量时，进行三水平荟萃分析，并使用漏斗图、二水平和三水平的Egger检验来评估发表偏倚。结果：中央顶叶区在整个、早、晚时间窗的总效应量显著，而其他脑区和时间窗的总效应量无统计学意义。结论：中央顶叶LPP是情绪调节（尤其是认知重评）的可靠电生理指标，且这种情绪调节的差异在早、晚时间窗更为明显。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Brain Research Bulletin 医学-神经科学

CiteScore

6.90

自引率

2.60%

发文量

253

审稿时长

67 days

期刊介绍： The Brain Research Bulletin (BRB) aims to publish novel work that advances our knowledge of molecular and cellular mechanisms that underlie neural network properties associated with behavior, cognition and other brain functions during neurodevelopment and in the adult. Although clinical research is out of the Journal''s scope, the BRB also aims to publish translation research that provides insight into biological mechanisms and processes associated with neurodegeneration mechanisms, neurological diseases and neuropsychiatric disorders. The Journal is especially interested in research using novel methodologies, such as optogenetics, multielectrode array recordings and life imaging in wild-type and genetically-modified animal models, with the goal to advance our understanding of how neurons, glia and networks function in vivo.