{"title":"The Effects of 6-Month Exclusive Breastfeeding on Febrile Seizure: A Systematic Review and Meta-Analysis.","authors":"Bahareh Vard, Maryam Yazdi, Zahra Akbarzadeh, Shiva Rouzbahani, Roya Kelishadi","doi":"10.22037/ijcn.v19i4.45672","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>Prior research investigating the variance in febrile seizure (FS) incidence between 6-month-old exclusively breastfed (EBF) and partially breastfed children has yielded inconsistent findings. To fill this void, this study conducted a systematic review and meta-analysis.</p><p><strong>Materials & methods: </strong>This study performed a search across electronic databases, including PubMed, Scopus, the Cochrane Library, and Google Scholar without any restrictions, from the year 2000 up to January 2024.</p><p><strong>Results: </strong>Thirteen studies were reviewed. Regarding six articles (data number=1876753) used in the meta-analysis, EBF (OR=0.65, 95% CI: 0.50, 0.85) and partial breastfeeding (OR=0.92, 96% CI: 0.91, 94) were both significantly associated with lower risks of FS. However, the association in the EBF group was stronger.</p><p><strong>Conclusion: </strong>Breastfeeding positively affects lowering the risk of FS. Encouraging mothers to breastfeed and implementing preventive strategies can be beneficial for health policymakers in reducing the incidence of FS.</p>","PeriodicalId":14537,"journal":{"name":"Iranian Journal of Child Neurology","volume":"19 4","pages":"17-23"},"PeriodicalIF":1.0000,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12593140/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Iranian Journal of Child Neurology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22037/ijcn.v19i4.45672","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Objectives: Prior research investigating the variance in febrile seizure (FS) incidence between 6-month-old exclusively breastfed (EBF) and partially breastfed children has yielded inconsistent findings. To fill this void, this study conducted a systematic review and meta-analysis.
Materials & methods: This study performed a search across electronic databases, including PubMed, Scopus, the Cochrane Library, and Google Scholar without any restrictions, from the year 2000 up to January 2024.
Results: Thirteen studies were reviewed. Regarding six articles (data number=1876753) used in the meta-analysis, EBF (OR=0.65, 95% CI: 0.50, 0.85) and partial breastfeeding (OR=0.92, 96% CI: 0.91, 94) were both significantly associated with lower risks of FS. However, the association in the EBF group was stronger.
Conclusion: Breastfeeding positively affects lowering the risk of FS. Encouraging mothers to breastfeed and implementing preventive strategies can be beneficial for health policymakers in reducing the incidence of FS.