Optimizing cyclopean stimuli for the evaluation of stereo vision by steady-state visual evoked potentials.

IF 2.9 4区医学 Q2 OPHTHALMOLOGY

Documenta Ophthalmologica Pub Date : 2025-10-17 DOI:10.1007/s10633-025-10059-6

János Radó, Eszter Mikó-Baráth, Péter Hegyi, Vanda A Nemes, Gábor Jandó, Péter Buzás

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引用次数: 0

Abstract

Purpose: This study aimed to optimize dynamic random dot correlogram (DRDC) and stereogram (DRDS) stimuli to evoke steady-state visual evoked potentials (ssVEP) on multiple EEG channels for the objective assessment of stereopsis.

Methods: EEG recordings were conducted on 22 healthy adults (mean age: 30.2 ± 5.8 years) while viewing cyclopean and control stimuli. DRDC and DRDS were presented at three temporal frequencies (0.9375, 1.875, and 3.75 cycles per second, cps) using anaglyphic channel separation. The ssVEP responses were analyzed using T²_circ statistical test to determine the most effective stimulus for eliciting significant cortical activity.

Results: DRDC at 1.875 cps evoked significant ssVEP responses in 93% of participants on at least one occipital electrode (O1, Oz, O2) and in 100% when including parietal-occipital electrodes. DRDS at similar frequencies also produced robust responses but required additional parietal electrode monitoring. Monocular control measurements confirmed that responses were stereo-specific.

Conclusions: DRDC at 1.875 cps was the most effective stimulus for objective electrophysiological assessment of stereopsis, demonstrating high reliability with minimal electrode setups. These findings support the integration of optimized ssVEP protocols into clinical assessments, particularly for non-verbal or pediatric populations.

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利用稳态视觉诱发电位优化立体视觉评价的独眼刺激。

目的：优化动态随机点相关图（DRDC）和立体图（DRDS）刺激在多个脑电通道上激发稳态视觉诱发电位（ssVEP），用于立体视觉的客观评价。方法：对22例健康成人（平均年龄：30.2±5.8岁）分别观察cyclopean和control刺激时的脑电图进行记录。DRDC和DRDS分别在3个时间频率（0.9375、1.875和3.75 cycles / s, cps）下进行分析。使用T2circ统计检验分析ssVEP的反应，以确定引起显著皮质活动的最有效刺激。结果：1.875 cps的DRDC在至少一个枕部电极（O1, Oz, O2）上诱发了93%的参与者显著的ssVEP反应，当包括顶叶-枕部电极时，这一比例为100%。相似频率的DRDS也产生了强大的响应，但需要额外的顶叶电极监测。单目控制测量证实了反应是立体特异性的。结论：1.875 cps的DRDC是立体视觉客观电生理评估的最有效刺激，在最小的电极设置下显示出高可靠性。这些发现支持将优化的ssVEP方案整合到临床评估中，特别是针对非语言或儿科人群。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Documenta Ophthalmologica 医学-眼科学

CiteScore

3.50

自引率

21.40%

发文量

审稿时长

>12 weeks

期刊介绍： Documenta Ophthalmologica is an official publication of the International Society for Clinical Electrophysiology of Vision. The purpose of the journal is to promote the understanding and application of clinical electrophysiology of vision. Documenta Ophthalmologica will publish reviews, research articles, technical notes, brief reports and case studies which inform the readers about basic and clinical sciences related to visual electrodiagnosis and means to improve diagnosis and clinical management of patients using visual electrophysiology. Studies may involve animals or humans. In either case appropriate care must be taken to follow the Declaration of Helsinki for human subject or appropriate humane standards of animal care (e.g., the ARVO standards on Animal Care and Use).