Efficacy of antimicrobial stewardship indicators in assessing the impact of a regional antibiotic therapy center in primary care and nursing homes.

IF 2.2 4区医学 Q2 INFECTIOUS DISEASES

Infectious diseases now Pub Date : 2025-10-09 DOI:10.1016/j.idnow.2025.105165

Renan Le Cras, Patricia Vidal, Patricia Pavese, Patrice François, Anna Sette, Philippe Lesprit

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Abstract

Objective: This study describes the implementation and short-term evolution of the antibiotherapy indicators selected by the Regional Antibiotherapy Center of Auvergne-Rhône-Alpes for utilization in primary care and nursing homes.

Material and methods: This retrospective observational study was based on public reimbursement data between 2021 and 2023. Seven indicators were selected for the community and eight for nursing homes.

Results: We observed positive trends for first-line antibiotics for female urinary tract infections (community: + 28 %, nursing homes: +18 %), treatment duration > 7 days (community: -7,8%; -13,4% for amoxicillin-clavulanic acid; nursing homes: -20,5%), fluoroquinolones in nursing homes (-16 %) and a combination of amoxicillin-clavulanic acid with metronidazole or amoxicillin in the community (-22 %). That said, total antibiotic consumption increased in the community (+16.5 %), while remaining stable in nursing homes.

Conclusion: This study identified areas for improvement in antibiotic therapy in our region. A longer follow-up will be necessary to assess the potential impact of initiatives such as ours on proper antibiotic use.

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抗菌药物管理指标在评估区域抗生素治疗中心在初级保健和养老院的影响中的功效。

目的：本研究描述了Auvergne-Rhône-Alpes区域抗生素治疗中心选择的抗生素治疗指标在初级保健和养老院使用的实施情况和短期演变。材料和方法：本回顾性观察性研究基于2021年至2023年的公共报销数据。社区选择了7个指标，养老院选择了8个指标。结果：我们观察到女性尿路感染一线抗生素治疗呈阳性趋势（社区：+ 28 %，养老院：+18 %），治疗持续时间 > 7天（社区：- 7.8%；阿莫西林-克拉维酸治疗：- 13.4%；养老院：- 20.5%），养老院氟喹诺酮类药物治疗（-16 %），社区阿莫西林-克拉维酸联合甲硝唑或阿莫西林治疗（-22 %）。也就是说，社区的抗生素总消费量增加了（+ 16.5% %），而疗养院的抗生素消费量保持稳定。结论：本研究确定了本地区抗生素治疗有待改进的领域。有必要进行更长时间的随访，以评估像我们这样的举措对正确使用抗生素的潜在影响。

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