Differences in response inhibition between medication-free patients with obsessive-compulsive disorder with and without sensory phenomena.

IF 1.8 4区心理学 Q2 PSYCHOLOGY

Journal of Neuropsychology Pub Date : 2025-10-11 DOI:10.1111/jnp.70016

Keitaro Murayama, Hirofumi Tomiyama, Kenta Sashikata, Mingi Kang, Aikana Ohno, Kenta Kato, Akira Matsuo, Tomohiro Nakao

引用次数: 0

Abstract

Obsessive-compulsive disorder (OCD) is a heterogeneous disorder, and approximately 70% of patients with OCD experience sensory phenomena (SP). Previous studies have revealed that patients with OCD exhibit a deficit in response inhibition (RI). However, few studies have investigated the relationship between SP and RI in patients with OCD. This study aimed to investigate differences in RI between non-comorbid, medication-free patients with OCD with and without SP. Thirty-seven patients with OCD with SP (OCD + SP), 27 without SP (OCD-noSP), and 50 controls (HCs) were compared in terms of RI using the stop-signal task. Both OCD groups had a deficit in RI compared with HCs, and no difference in RI was found between the OCD + SP and OCD-noSP groups. No correlation was observed between SP and stop-signal reaction time in the OCD + SP group. Our findings suggest that a deficit in RI is not related to SP in OCD.

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有无感觉现象的无药强迫症患者反应抑制的差异。

强迫症（OCD）是一种异质性疾病，大约70%的强迫症患者会经历感觉现象（SP）。先前的研究表明，强迫症患者表现出反应抑制（RI）的缺陷。然而，很少有研究调查强迫症患者SP和RI之间的关系。本研究旨在探讨无合并症、无药物的强迫症患者伴SP和不伴SP之间的RI差异。37例伴SP的强迫症患者（OCD + SP）、27例无SP的强迫症患者（OCD- nosp）和50例对照（hc）使用停止信号任务进行RI比较。与hc相比，两个OCD组的RI都有缺陷，OCD + SP组和OCD- nosp组之间的RI没有差异。OCD + SP组SP与停止信号反应时间无相关性。我们的研究结果表明，强迫症患者的RI缺陷与SP无关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Neuropsychology 医学-心理学

CiteScore

4.50

自引率

4.50%

发文量

审稿时长

>12 weeks

期刊介绍： The Journal of Neuropsychology publishes original contributions to scientific knowledge in neuropsychology including: • clinical and research studies with neurological, psychiatric and psychological patient populations in all age groups • behavioural or pharmacological treatment regimes • cognitive experimentation and neuroimaging • multidisciplinary approach embracing areas such as developmental psychology, neurology, psychiatry, physiology, endocrinology, pharmacology and imaging science The following types of paper are invited: • papers reporting original empirical investigations • theoretical papers; provided that these are sufficiently related to empirical data • review articles, which need not be exhaustive, but which should give an interpretation of the state of research in a given field and, where appropriate, identify its clinical implications • brief reports and comments • case reports • fast-track papers (included in the issue following acceptation) reaction and rebuttals (short reactions to publications in JNP followed by an invited rebuttal of the original authors) • special issues.