Health risk assessment of heavy metals in drinking water reservoirs of Yasuj Iran using Monte Carlo simulation and sensitivity analysis

IF 4.6 2区农林科学 Q2 CHEMISTRY, APPLIED

Journal of Food Composition and Analysis Pub Date : 2025-10-02 DOI:10.1016/j.jfca.2025.108398

Saeid Fallahizadeh , Seyed Nouredin Hosseini gousheh , Amin Hossaini motlagh , Mohammadreza Zarei , Negin Rahimi , Seyed Abdolmohammad Sadat

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引用次数: 0

Abstract

Heavy metals (HMs) in drinking water are a health hazard to humans as they induce a variety of diseases. In this study, the concentrations of HMs (As, Cd, Pb, Hg, Cu, and Zn) in 24 water samples collected from eight reservoirs of Yasuj (Iran) were analyzed using an inductively coupled plasma mass spectrometry. Potential carcinogenic and non-carcinogenic health risks due to the ingestion of HMs in the water samples were also assessed estimating hazard quotient (HQ), hazard index (HI) and cancer risk (CR). The average concentrations (μg/L) of HMs were found to be 2.53 (As), 0.33 (Cd), 13.94 (Cu), 2.97 (Pb), 0.99 (Hg), and 258.65 (Zn). All HMs had HQ values under 1 for all age categories, but the average value of HI estimated for infants was above safety limits at 1.21. The average values of CRs were estimated as 2.18 × 10⁻⁴ (As) and 1.13 × 10⁻⁴ (Cd). Monte Carlo simulation showed that HM concentrations are mostly acceptable, but that infants are in considerable health jeopardy. The study thus calls for continuous monitoring and risk mitigation measures to protect these vulnerable sections against the prospective long-haul impacts of heavy metal exposure via drinking water.

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基于蒙特卡罗模拟和敏感性分析的伊朗Yasuj饮用水水库重金属健康风险评价

饮用水中的重金属会引起多种疾病，对人类健康造成危害。本研究采用电感耦合等离子体质谱法分析了伊朗Yasuj 8个水库24个水样中重金属（As、Cd、Pb、Hg、Cu和Zn）的浓度。同时对水样中HMs的潜在致癌性和非致癌性健康风险进行了评估，评估了危害商数（HQ）、危害指数（HI）和致癌风险（CR）。HMs的平均浓度（μ L）分别为：As（2.53）、Cd（0.33）、Cu（13.94）、Pb（2.97）、Hg（0.99）和Zn（258.65）。所有年龄组的HMs的HQ值都在1以下，但婴儿的平均HI值高于安全限值1.21。cr的平均值估计为2.18 × 10−4 （as）和1.13 × 10−4 （Cd）。蒙特卡罗模拟表明，HM浓度大多是可以接受的，但婴儿的健康受到相当大的危害。因此，该研究呼吁持续监测和采取风险缓解措施，以保护这些脆弱区域免受通过饮用水接触重金属的可能的长期影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Food Composition and Analysis 工程技术-食品科技

CiteScore

6.20

自引率

11.60%

发文量

601

审稿时长

53 days

期刊介绍： The Journal of Food Composition and Analysis publishes manuscripts on scientific aspects of data on the chemical composition of human foods, with particular emphasis on actual data on composition of foods; analytical methods; studies on the manipulation, storage, distribution and use of food composition data; and studies on the statistics, use and distribution of such data and data systems. The Journal''s basis is nutrient composition, with increasing emphasis on bioactive non-nutrient and anti-nutrient components. Papers must provide sufficient description of the food samples, analytical methods, quality control procedures and statistical treatments of the data to permit the end users of the food composition data to evaluate the appropriateness of such data in their projects. The Journal does not publish papers on: microbiological compounds; sensory quality; aromatics/volatiles in food and wine; essential oils; organoleptic characteristics of food; physical properties; or clinical papers and pharmacology-related papers.