Maria Fernanda Alvarez-Alatriste, Andrea Gallardo-Villamil, Cristian M Salgado-Flores, Carrie C Coughlin, Liza Siegel, Leah Lalor, Kelly M Cordoro, Christine Wong, María Teresa García-Romero
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Abstract
This multicenter, descriptive, retrospective study conducted at four centers aimed to describe the clinical, histological, and/or genetic characteristics and clinical course of pediatric patients with a history of Langerhans cell histiocytosis (LCH) who later developed eruptive melanocytic nevi from 2003 to 2023. Of seven patients diagnosed with LCH (average age of 18 months, range 0-96), five patients showed multisystem involvement affecting low-risk organs, while two presented with single-system disease localized to the skin. Agminated eruptive melanocytic nevi developed at an average of 48 months (SD ± 27.37) after initial LCH diagnosis, predominating on the trunk, groin, and upper extremities (in three patients at sites of previous LCH lesions). Agminated eruptive melanocytic nevi may appear in patients with LCH; further research is required to achieve a more comprehensive understanding.
期刊介绍：
Pediatric Dermatology answers the need for new ideas and strategies for today''s pediatrician or dermatologist. As a teaching vehicle, the Journal is still unsurpassed and it will continue to present the latest on topics such as hemangiomas, atopic dermatitis, rare and unusual presentations of childhood diseases, neonatal medicine, and therapeutic advances. As important progress is made in any area involving infants and children, Pediatric Dermatology is there to publish the findings.
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