Javier García Fernández, José Pablo Suárez-Llanos, Cristina Lorenzo González, Elena Márquez Mesa, María Araceli García Núñez, Maria Demelza Farrais Luis, Manuel Enrique Fuentes Ferrer
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引用次数: 0
Abstract
Introduction: Malnutrition is a well-established negative prognostic factor in hospitalized patients, contributing to increased morbidity and mortality. The CIPA (Control of Food Intake, Protein, and Anthropometry) screening tool was developed to identify patients at nutritional risk and to predict adverse clinical outcomes across both surgical and non-surgical populations. This study aimed to evaluate the prognostic value of the CIPA tool in routine clinical practice by analyzing its association with key clinical outcomes since its implementation at our center in 2014.
Materials and methods: We conducted a retrospective analysis of inpatients screened with the CIPA tool between 2014 and 2022 in a tertiary care hospital. The association between CIPA screening results and clinical outcomes-including 3- and 6-month mortality, early hospital readmission, and length of stay-was assessed, with a particular focus on patients with active oncological disease. Regression analyses were adjusted for age, sex, admitting department, and type of admission.
Results: A total of 30,581 patients were included, of whom 31.4% screened positive for malnutrition using the CIPA tool. CIPA-positive patients had significantly higher mortality at 3 months (adjusted OR 3.02; 95% CI: 2.78-3.30; p < 0.001) and at 6 months (adjusted OR 2.69; 95% CI: 2.49-2.91; p < 0.001). They also exhibited increased rates of early readmission (adjusted OR 1.43; 95% CI: 1.34-1.53; p < 0.001) and a longer median hospital stay (β = 0.25; 95% CI: 0.23-0.27; p < 0.001).
Discussion: In this large, real-world cohort, the CIPA nutritional screening tool was a robust predictor of poorer clinical outcomes among hospitalized patients with positive screening results. These findings support the utility of CIPA screening for early identification of high-risk patients, enabling targeted nutritional interventions to potentially mitigate adverse outcomes.
导言：营养不良是住院患者的一个公认的不良预后因素，有助于增加发病率和死亡率。CIPA（食物摄入、蛋白质和人体测量控制）筛查工具的开发是为了识别有营养风险的患者，并预测手术和非手术人群的不良临床结果。本研究旨在通过分析CIPA工具自2014年在我中心实施以来与主要临床结果的关系，评估其在常规临床实践中的预后价值。材料和方法：我们对一家三级保健医院2014年至2022年间使用CIPA工具筛查的住院患者进行了回顾性分析。CIPA筛查结果与临床结果（包括3个月和6个月死亡率、早期再入院和住院时间）之间的关系被评估，特别关注活动性肿瘤疾病患者。回归分析根据年龄、性别、入院部门和入院类型进行调整。结果：共纳入30,581例患者，其中31.4%使用CIPA工具筛查为营养不良阳性。CIPA阳性患者在3 个月时的死亡率明显更高（调整后OR为3.02；95% CI为2.78-3.30;p p p β = 0.25；95% CI为0.23-0.27;p ）讨论：在这个庞大的真实世界队列中，CIPA营养筛查工具是筛查结果阳性的住院患者临床预后较差的可靠预测因子。这些发现支持了CIPA筛查对高危患者早期识别的效用，使有针对性的营养干预能够潜在地减轻不良后果。
期刊介绍：
No subject pertains more to human life than nutrition. The aim of Frontiers in Nutrition is to integrate major scientific disciplines in this vast field in order to address the most relevant and pertinent questions and developments. Our ambition is to create an integrated podium based on original research, clinical trials, and contemporary reviews to build a reputable knowledge forum in the domains of human health, dietary behaviors, agronomy & 21st century food science. Through the recognized open-access Frontiers platform we welcome manuscripts to our dedicated sections relating to different areas in the field of nutrition with a focus on human health.
Specialty sections in Frontiers in Nutrition include, for example, Clinical Nutrition, Nutrition & Sustainable Diets, Nutrition and Food Science Technology, Nutrition Methodology, Sport & Exercise Nutrition, Food Chemistry, and Nutritional Immunology. Based on the publication of rigorous scientific research, we thrive to achieve a visible impact on the global nutrition agenda addressing the grand challenges of our time, including obesity, malnutrition, hunger, food waste, sustainability and consumer health.
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