Butyric and valeric glycerides blend prevents adverse impacts of coccidiosis challenge in broiler chickens

IF 4.2 1区农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE

Poultry Science Pub Date : 2025-09-22 DOI:10.1016/j.psj.2025.105879

Sm Mostafizur Rahaman Sumon , Alip Kumar , Di Wu , Shu-Biao Wu , Kosar Gharib-Naseri

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引用次数: 0

Abstract

Organic acids are well known for their antibacterial and antifungal effects, but their potential efficacy against coccidian parasites remains underexplored. The aim of the study was to evaluate the effects of a butyric and valeric glyceride blend (BVg) in mitigating the adverse impacts of coccidiosis in broiler chickens. A total of 960 mixed-sex d-old Cobb 500 chicks were randomly allocated to five treatments with 12 replicates, each containing 16 birds. The five treatments were: non-challenged control (NC); coccidiosis challenged control (CC); CC+ BVg (BV; 500, 500, and 250 g/ton in the starter, grower and finisher phases, respectively); CC + anticoccidial salinomycin, 60 g/t (AntS); and CC + salinomycin + BVg (ABV). Coccidiosis challenge was induced on d9 via oral gavage with Eimeria spp. Performance parameters were determined on days 8, 19, 28 and 35. Lesion scoring and ileal digesta sampling was performed on d16 and excreta samples were collected on d20 for oocyst enumeration. One-way ANOVA followed by Tukey’s test to separate means was applied to normally distributed data, while the Kruskal-Wallis test was used for data that did not meet the normality assumption. The results showed that BVg supplementation significantly improved feed conversion ratio (FCR) during starter (d0-8), grower (d8-19) and overall study (d0-35) periods compared to the CC group (P < 0.05). BVg supplementation also numerically improved flock uniformity and significantly reduced oocyst counts (P < 0.05) and duodenal lesions (P < 0.05) compared to the CC group. Additionally, BVg inclusion shifted hock burn lesions and tibia length values from the CC group towards the NC and ABV groups, respectively. These findings suggest that BVg may offer a promising nutritional strategy to mitigate the adverse effects of coccidiosis, reducing oocyst loads and gut lesions, while supporting the feed efficiency and hock burn lesions of broiler chickens.

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丁酸甘油酯和戊酸甘油酯混合可预防肉鸡球虫病侵袭的不利影响

有机酸以其抗菌和抗真菌作用而闻名，但其对球虫寄生虫的潜在功效仍未得到充分研究。本研究的目的是评价丁酸和戊酸甘油酯混合物（BVg）减轻肉鸡球虫病不良影响的效果。选取960只雌雄混合d龄Cobb 500雏鸡，随机分为5个处理，每处理12个重复，每个重复16只。5个处理分别为：无挑战对照（NC）；球虫病挑战对照；CC+ BVg（发酵剂、生长剂和育成剂阶段的BV分别为500、500和250 g/吨）；CC +抗球虫盐霉素，60 g/t (AntS)；CC +盐碱霉素+ BVg （ABV）。第9天采用艾美耳球虫灌胃诱导球虫感染，第8、19、28、35天测定球虫性能参数。第16天进行病变评分和回肠食糜取样，第20天收集排泄物标本进行卵囊计数。正态分布的数据采用单因素方差分析和Tukey的均数分离检验，不符合正态性假设的数据采用Kruskal-Wallis检验。结果表明：与CC组相比，添加BVg显著提高了发酵期（d0 ~ 8）、生长期（d8 ~ 19）和整个研究期（d0 ~ 35）的饲料系数（FCR）（P < 0.05）。与CC组相比，添加BVg还在数值上改善了鸡群均匀性，显著减少了卵囊计数（P < 0.05）和十二指肠病变（P < 0.05）。此外，BVg包含将飞节烧伤病变和胫骨长度值分别从CC组转移到NC组和ABV组。这些发现表明，BVg可能是一种有希望的营养策略，可以减轻球虫病的不良影响，减少卵囊负荷和肠道损伤，同时支持肉鸡的饲料效率和飞节烧伤。

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来源期刊

Poultry Science 农林科学-奶制品与动物科学

CiteScore

7.60

自引率

15.90%

发文量

审稿时长

94 days

期刊介绍： First self-published in 1921, Poultry Science is an internationally renowned monthly journal, known as the authoritative source for a broad range of poultry information and high-caliber research. The journal plays a pivotal role in the dissemination of preeminent poultry-related knowledge across all disciplines. As of January 2020, Poultry Science will become an Open Access journal with no subscription charges, meaning authors who publish here can make their research immediately, permanently, and freely accessible worldwide while retaining copyright to their work. Papers submitted for publication after October 1, 2019 will be published as Open Access papers. An international journal, Poultry Science publishes original papers, research notes, symposium papers, and reviews of basic science as applied to poultry. This authoritative source of poultry information is consistently ranked by ISI Impact Factor as one of the top 10 agriculture, dairy and animal science journals to deliver high-caliber research. Currently it is the highest-ranked (by Impact Factor and Eigenfactor) journal dedicated to publishing poultry research. Subject areas include breeding, genetics, education, production, management, environment, health, behavior, welfare, immunology, molecular biology, metabolism, nutrition, physiology, reproduction, processing, and products.