Longitudinal habituation and novelty detection neural responses from infancy to early childhood in The Gambia and UK

Abstract

As infants and young children learn from and respond to their environment, their development is driven by their ability to filter out irrelevant stimuli and respond to salient stimuli. While sources and types of stimuli vary across cultural contexts, research to understand the neural mechanisms of these behaviors have largely focused on relatively homogeneous populations in high income settings. To address this lack of diverse representation the Brain Imaging for Global health project (BRIGHT) collected longitudinal data in The Gambia (N = 204) and the UK (N = 61). Here we present results of the Habituation and Novelty Detection (HaND) fNIRS neuroimaging task. Gambian infants showed persistent response suppression (Habituation) at all visits (from 5mo to 60mo) while Novelty Detection was only observed once infants reached 18 and 24mo. In the UK, infants only showed persistent habituation from 5 to 12mo, while the response was not evident at 18 and 24mo. Furthermore, in contrast to The Gambia, alongside the habituation patterns observed Uk infants showed novelty detection from 5 to 12mo. This is the first longitudinal description of the HaND response in individuals from different contextual backgrounds across such a broad age range and number of time points, revealing different patterns of specialization in The Gambia and UK.