Ancient alleles drive contemporary climate adaptation in an alpine plant

IF 45.8 1区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

Science Pub Date : 2025-10-02 DOI:10.1126/science.adp5717

Simone Fior, Hirzi Luqman, Mathias Scharmann, Aksel Pålsson, Jennifer de Jonge, Stefan Zoller, Niklaus Zemp, Domenico Gargano, Daniel Wegmann, Alex Widmer

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Abstract

Adaptive evolution is key for species to persist in a warming climate. However, how adaptive genetic variants arise and shape both past and future evolutionary trajectories remains largely unknown. In this work, we integrate genomics with functional and ecological assays to unravel the evolutionary history and adaptive potential of alleles governing adaptation to climate through flowering time in an Alpine carnation. We reveal that “warm” and “cold” alleles of the flowering inhibitor CENTRORADIALIS (DsCEN/2) originated through recombination of highly divergent haplotypes during the carnation radiation, implicating ancestral variation in seeding climate-adaptive alleles. These alleles survived in glacial refugia before mediating the species’ range expansion in response to postglacial warming. We predict that, by recapitulating past evolution, warm alleles will continue to facilitate adaptation under future climate change.

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古等位基因驱动高山植物的当代气候适应

适应性进化是物种在气候变暖中生存的关键。然而，适应性基因变异是如何产生和塑造过去和未来的进化轨迹的，在很大程度上仍然是未知的。在这项工作中，我们将基因组学与功能和生态分析相结合，揭示了高山康乃馨通过开花时间适应气候的等位基因的进化史和适应潜力。我们发现，开花抑制剂CENTRORADIALIS （DsCEN/2）的“温暖”和“寒冷”等位基因起源于康乃馨辐射期间高度分化的单倍型重组，暗示了种子气候适应等位基因的祖先变异。这些等位基因在冰期后变暖导致物种范围扩大之前，在冰川避难所中存活了下来。我们预测，通过回顾过去的进化，温暖等位基因将继续促进对未来气候变化的适应。

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来源期刊

Science 综合性期刊-综合性期刊

CiteScore

61.10

自引率

0.90%

发文量

审稿时长

2.1 months

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