Approach bias modification training reduces gaming severity and improves brain network topology in internet gaming disorder

IF 3.6 2区医学 Q1 PSYCHOLOGY, CLINICAL

Addictive behaviors Pub Date : 2025-09-12 DOI:10.1016/j.addbeh.2025.108494

Xin Luo , Shunchao He , Jiejie Fu , Yi-Sheng Dong , Bo Yang , Meiting Wei , Yandan Li , Zhushan Zhouzhang , Xuzhou Li , Fuming Xu , Guang-Heng Dong

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引用次数: 0

Abstract

Background

Patients with internet gaming disorder (IGD) suffer from an imbalance of over-integrated and weakly dissociated functional brain networks. Approach bias modification training (ApBMt) has been used to correct patients’ automatic approach biases to addictive stimuli; however, research exploring changes in brain network topology is limited.

Methods

Seventy subjects were randomly assigned to the approach-avoidance task (AAT) group or the sham-AAT group, and 57 subjects (AAT, 30; sham-AAT, 27) completed the entire procedure, which included pretests, AAT/sham-AAT interventions, and posttests. Behavioral and resting-state fMRI data were collected before and after the tests. This study aimed to investigate the effects of ApBMt on topological changes in resting functional brain networks in patients with IGD and explore the relationship between these network changes and behavioral indicators of addiction severity.

Results

Repeated-measures ANOVA of the behavioral data showed that the AAT group had significant score reductions after ApBMt. Imaging data revealed significant decreases in brain network over-integration and increases in segregation of the fronto-parietal network (FPN) and the cingulo-opercular network (CON). Additionally, a positive correlation was found between the post-pre difference in DSM-5 scores and the post-pre difference in nodal efficiency (Ne) in the anterior prefrontal cortex (aPFC).

Conclusions

The findings of this study demonstrate that ApBMt effectively reduces the severity of IGD, along with associated changes in brain network topology, such as enhanced segregation and decreased over-integration. However, it is important to highlight that the neurobiological changes observed are correlated with the reduction in IGD severity, but causality cannot be established. Further research is necessary to better understand the clinical potential of ApBMt in treating IGD, either as a stand-alone intervention or in combination with other therapeutic approaches.

查看原文本刊更多论文

方法偏差修正训练降低了网络游戏障碍的游戏严重程度，改善了网络拓扑结构。

背景：网络游戏障碍（IGD）患者表现为过度整合和弱分离的脑功能网络失衡。趋近偏差修正训练（ApBMt）已被用于纠正患者对成瘾刺激的自动趋近偏差；然而，探索大脑网络拓扑结构变化的研究是有限的。方法：将70名受试者随机分为回避回避任务组（AAT）和假回避回避任务组，57名受试者（AAT 30名；假回避回避任务27名）完成了包括前测、AAT/假回避回避干预和后测在内的整个过程。在测试前后收集行为和静息状态的fMRI数据。本研究旨在探讨ApBMt对IGD患者静息脑功能网络拓扑变化的影响，并探讨这些网络变化与成瘾严重程度行为指标的关系。结果：行为数据的重复测量方差分析显示，AAT组在ApBMt后得分显著降低。成像数据显示，脑网络过度整合显著减少，额顶叶网络（FPN）和扣谷-眼窝网络（CON）分离增加。此外，DSM-5评分前后差异与前前额叶皮质（aPFC）节点效率（Ne）差异呈正相关。结论：本研究的结果表明，ApBMt有效降低了IGD的严重程度，以及相关的脑网络拓扑变化，如增强隔离和减少过度整合。然而，重要的是要强调，观察到的神经生物学变化与IGD严重程度的降低有关，但因果关系无法确定。需要进一步研究以更好地了解ApBMt治疗IGD的临床潜力，无论是作为单独干预还是与其他治疗方法联合使用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Addictive behaviors 医学-药物滥用

CiteScore

8.40

自引率

4.50%

发文量

283

审稿时长

46 days

期刊介绍： Addictive Behaviors is an international peer-reviewed journal publishing high quality human research on addictive behaviors and disorders since 1975. The journal accepts submissions of full-length papers and short communications on substance-related addictions such as the abuse of alcohol, drugs and nicotine, and behavioral addictions involving gambling and technology. We primarily publish behavioral and psychosocial research but our articles span the fields of psychology, sociology, psychiatry, epidemiology, social policy, medicine, pharmacology and neuroscience. While theoretical orientations are diverse, the emphasis of the journal is primarily empirical. That is, sound experimental design combined with valid, reliable assessment and evaluation procedures are a requisite for acceptance. However, innovative and empirically oriented case studies that might encourage new lines of inquiry are accepted as well. Studies that clearly contribute to current knowledge of etiology, prevention, social policy or treatment are given priority. Scholarly commentaries on topical issues, systematic reviews, and mini reviews are encouraged. We especially welcome multimedia papers that incorporate video or audio components to better display methodology or findings. Studies can also be submitted to Addictive Behaviors? companion title, the open access journal Addictive Behaviors Reports, which has a particular interest in ''non-traditional'', innovative and empirically-oriented research such as negative/null data papers, replication studies, case reports on novel treatments, and cross-cultural research.