T Brandscher, J. Hoisington, A. Shelow, C. Myers, J. Thomas, D. A. Lopez
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引用次数: 0
Abstract
Per- and Polyfluoroalkyl Substances (PFAS) pose significant analytical challenges due to their widespread occurrence, complex sample matrices, and low detection limits. EPA Method 1633, finalized in early 2024, provides a comprehensive protocol for quantifying 40 PFAS compounds in aqueous, solid, and tissue matrices. However, the method's reliance on dispersive graphitized carbon black (GCB) cleanup and large-volume solid-phase extraction (SPE) steps can be time-consuming, variable, and prone to clogging—particularly in non-drinking water rich in suspended solids as well as food and tissue matrices.
To address these limitations, we developed an improved dual bed SPE cartridge combining weak anion exchange (WAX) and GCB sorbents with an integrated Filter Aid. This design eliminates the need for manual glass wool packing and dispersive cleanup steps
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