Applicability of Hibiscus sabdariffa L. Extract With Anti-Inflammatory Potential in Human Health: A Review

Abstract

Studies demonstrate the health benefits of H. sabdariffa L., highlighting its anti-inflammatory activity. Therefore, it is essential to expand studies on this plant and its various applications, aiming to maximize its benefits for human health, especially through the use of the bioactive compounds present in Hibiscus sabdariffa L. To prepare this review article, we conducted a literature search through virtual libraries of scientific articles, such as LILACS, PUBMED, and BVS, using the following descriptors: Hibiscus sabdariffa L. and anti-inflammatory. The selected publications cover the period 2019 to 2024 (5 years). A total of 25 articles were found, distributed as follows: PUBMED: 24 articles, of which 11 were excluded. The exclusion was because these articles did not meet the research objective or were review articles that did not meet the established criteria. No articles were found in the LILACS database, indicating that the search did not return relevant results within the search criteria. One article was found in the VHL database, but it was excluded due to duplication with an article already found in the PUBMED database. Analysis of the studies selected in the scientific database highlights the benefits of using Hibiscus sabdariffa L. in the treatment of various pathologies, such as degenerative diseases, intestinal dysfunctions, and atherosclerosis, among others, with a particular emphasis on its anti-inflammatory activities. However, the results did not demonstrate benefits in a study focused on wound healing, indicating that further studies are needed to investigate its specific application.