Prescribing patterns of psychotropic medications among people living with dementia after disasters.

IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY
Innovation in Aging Pub Date : 2025-06-18 eCollection Date: 2025-08-01 DOI:10.1093/geroni/igaf064
Sue Anne Bell, John P Donnelly, Muhammad Ghous, Shrathinth Venkatesh, Adriana Rojas, Antoinette B Coe
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引用次数: 0

Abstract

Background and objectives: Disasters can worsen behavioral symptoms in people living with dementia, leading to disorientation, anxiety, and paranoia. In such situations, psychotropic medications may be inappropriately used to manage these symptoms. This study estimated the receipt of new, or changes to existing, psychotropic prescription medications post-disaster among fee-for-service Medicare beneficiaries with a dementia diagnosis.

Research design and methods: Medicare administrative claims data were used to examine the relationship between hurricane exposure and receipt of antipsychotic prescriptions among people living with dementia with no prior use. The primary outcome was a daily count of new psychotropic prescriptions per beneficiary, from Part D claims, residing in exposed and unexposed counties 12 months after the hurricane landfall. The secondary outcome was a daily count of increases in the dosage of psychotropic prescriptions. Federal Emergency Management Agency disaster declarations were used to determine disaster-exposed groups.

Results: A total of 70 307 traditional fee-for-service beneficiaries with a dementia diagnosis were included in the study. In analyses adjusted for age, sex, race/ethnicity, Part D low-income subsidy status, rurality and number of Elixhauser comorbidities conducted over a 12-month period following the three hurricanes, beneficiaries exposed to the hurricanes had a 10% higher rate of starting new antipsychotic prescriptions compared to those in unexposed counties (IRR: 1.10, 95% CI: 1.04-1.17). Analyses conducted by individual hurricanes revealed substantial differences, with higher rates of initiating antipsychotics following Hurricane Harvey (IRR: 1.21, 95% CI: 1.07-1.36), and no change after Hurricanes Irma (IRR: 0.97, 95% CI: 0.88-1.08) and Florence (IRR: 0.92, 95% CI: 0.80-1.05).

Discussion and implications: Psychotropic prescribing increased after Hurricane Harvey but not after Irma or Florence, suggesting context-specific factors may influence clinical responses during disasters. Our findings highlight the importance of incorporating person-centered care and appropriate behavioral health responses into disaster preparedness planning for the dementia population.

灾害后痴呆症患者的精神药物处方模式。
背景和目的:灾难会加重痴呆症患者的行为症状,导致定向障碍、焦虑和偏执。在这种情况下,精神药物可能不适当地用于控制这些症状。这项研究估计了在诊断为痴呆症的按服务收费的医疗保险受益人中,灾后接受新的或改变现有的精神处方药的情况。研究设计和方法:医疗保险行政索赔数据用于检查飓风暴露与痴呆患者未使用过抗精神病药物处方之间的关系。主要结果是在飓风登陆12个月后,居住在受灾县和未受灾县的D部分索赔中,每个受益人每天新开精神药物处方的数量。次要结果是每日精神药物处方剂量增加的计数。联邦紧急事务管理局的灾害声明被用来确定受灾害影响的群体。结果:共有70307名诊断为痴呆症的传统收费服务受益人被纳入研究。在对年龄、性别、种族/民族、D部分低收入补贴状况、农村状况和Elixhauser合并症数量进行调整的分析中,在三次飓风之后的12个月内,与未暴露于飓风的县相比,暴露于飓风的受益人开始新的抗精神病药物处方的比率高出10% (IRR: 1.10, 95% CI: 1.94 -1.17)。对单个飓风进行的分析显示了实质性的差异,飓风哈维(IRR: 1.21, 95% CI: 1.07-1.36)后抗精神病药物的启动率较高,飓风Irma (IRR: 0.97, 95% CI: 0.88-1.08)和飓风Florence (IRR: 0.92, 95% CI: 0.80-1.05)后没有变化。讨论和启示:精神药物处方在飓风哈维后增加,但在飓风厄玛或佛罗伦萨后没有增加,这表明具体环境因素可能影响灾害期间的临床反应。我们的研究结果强调了将以人为本的护理和适当的行为健康反应纳入痴呆症人群的备灾计划的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Innovation in Aging
Innovation in Aging GERIATRICS & GERONTOLOGY-
CiteScore
4.10
自引率
0.00%
发文量
72
审稿时长
15 weeks
期刊介绍: Innovation in Aging, an interdisciplinary Open Access journal of the Gerontological Society of America (GSA), is dedicated to publishing innovative, conceptually robust, and methodologically rigorous research focused on aging and the life course. The journal aims to present studies with the potential to significantly enhance the health, functionality, and overall well-being of older adults by translating scientific insights into practical applications. Research published in the journal spans a variety of settings, including community, clinical, and laboratory contexts, with a clear emphasis on issues that are directly pertinent to aging and the dynamics of life over time. The content of the journal mirrors the diverse research interests of GSA members and encompasses a range of study types. These include the validation of new conceptual or theoretical models, assessments of factors impacting the health and well-being of older adults, evaluations of interventions and policies, the implementation of groundbreaking research methodologies, interdisciplinary research that adapts concepts and methods from other fields to aging studies, and the use of modeling and simulations to understand factors and processes influencing aging outcomes. The journal welcomes contributions from scholars across various disciplines, such as technology, engineering, architecture, economics, business, law, political science, public policy, education, public health, social and psychological sciences, biomedical and health sciences, and the humanities and arts, reflecting a holistic approach to advancing knowledge in gerontology.
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