Alien Hand: Current Research Trends.

IF 5.2 2区医学 Q1 CLINICAL NEUROLOGY

Current Neurology and Neuroscience Reports Pub Date : 2025-09-19 DOI:10.1007/s11910-025-01449-z

Victor W Mark

{"title":"Alien Hand: Current Research Trends.","authors":"Victor W Mark","doi":"10.1007/s11910-025-01449-z","DOIUrl":null,"url":null,"abstract":"Purpose of review: This article reviews alien hand, a neurological disorder that causes involuntary limb movements that appear to be purposeful. This review outlines the history that identified the three widely accepted forms of alien hand and their distinct clinical and neuroimaging findings. This material summarizes behavioral disturbances that can occur with alien hand but are seldom addressed in a single review article, including propensity for self-injury, pathological sexual behavior, alien hand activities during sleep, and communication disturbances of alien Quality. The article then presents other paroxysmal, involuntary disturbances that are not usually considered to be alien hand, despite their appearing to be purposeful. Finally, this article reviews all PubMed-listed articles from 2020 to mid-2025 that addressed either alien hand or limb, or anarchic hand, for trends in understanding and treating this illness.Recent findings: Meritorious advances in recent years included proposed checklists for the component behaviors for diagnosing alien hand, structured interviews for querying the patients' experiences, and demonstrating white matter cerebral damage that extends far beyond the lesion boundaries that are identifiable on conventional structural brain MRI. This review summarizes the diversity of the presentations of alien hand. Many behaviors that are encompassed by alien hand are not so far explained by clinical or experimental brain MRI findings.","PeriodicalId":10831,"journal":{"name":"Current Neurology and Neuroscience Reports","volume":"25 1","pages":"63"},"PeriodicalIF":5.2000,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449344/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Neurology and Neuroscience Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11910-025-01449-z","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose of review: This article reviews alien hand, a neurological disorder that causes involuntary limb movements that appear to be purposeful. This review outlines the history that identified the three widely accepted forms of alien hand and their distinct clinical and neuroimaging findings. This material summarizes behavioral disturbances that can occur with alien hand but are seldom addressed in a single review article, including propensity for self-injury, pathological sexual behavior, alien hand activities during sleep, and communication disturbances of alien Quality. The article then presents other paroxysmal, involuntary disturbances that are not usually considered to be alien hand, despite their appearing to be purposeful. Finally, this article reviews all PubMed-listed articles from 2020 to mid-2025 that addressed either alien hand or limb, or anarchic hand, for trends in understanding and treating this illness.

Recent findings: Meritorious advances in recent years included proposed checklists for the component behaviors for diagnosing alien hand, structured interviews for querying the patients' experiences, and demonstrating white matter cerebral damage that extends far beyond the lesion boundaries that are identifiable on conventional structural brain MRI. This review summarizes the diversity of the presentations of alien hand. Many behaviors that are encompassed by alien hand are not so far explained by clinical or experimental brain MRI findings.

Abstract Image

查看原文本刊更多论文

外星之手：当前的研究趋势。

综述目的：这篇文章回顾了异手症，一种神经系统疾病，引起非自愿的肢体运动，似乎是有目的的。这篇综述概述了三种被广泛接受的异手症的历史及其独特的临床和神经影像学发现。本材料总结了异手症可能发生的行为障碍，但很少在一篇综述文章中提到，包括自残倾向、病理性行为、睡眠中的异手活动和异质沟通障碍。文章随后提出了其他突发性，不自主的干扰，通常不被认为是异手，尽管他们似乎是有目的的。最后，本文回顾了从2020年到2025年中期所有pubmed列出的关于异手或肢体或无政府手的文章，以了解和治疗这种疾病的趋势。最近的发现：近年来值得称赞的进展包括提出了用于诊断异手症的组成行为检查表，用于查询患者经历的结构化访谈，以及证明白质脑损伤远远超出了常规脑结构MRI可识别的病变边界。本文综述了异手症表现形式的多样性。到目前为止，临床或实验脑MRI的发现还不能解释许多与异手有关的行为。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Current Neurology and Neuroscience Reports 医学-临床神经学

CiteScore

9.20

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Current Neurology and Neuroscience Reports provides in-depth review articles contributed by international experts on the most significant developments in the field. By presenting clear, insightful, balanced reviews that emphasize recently published papers of major importance, the journal elucidates current and emerging approaches to the diagnosis, treatment, management, and prevention of neurological disease and disorders. Presents the views of experts on current advances in neurology and neuroscience Gathers and synthesizes important recent papers on the topic Includes reviews of recently published clinical trials, valuable web sites, and commentaries from well-known figures in the field.