Health awareness correlates with whole-brain gray matter volume in healthy adults

IF 3.7 3区医学 Q2 NEUROSCIENCES

Brain Research Bulletin Pub Date : 2025-09-12 DOI:10.1016/j.brainresbull.2025.111547

Keisuke Kokubun , Kiyotaka Nemoto , Yoshinori Yamakawa

引用次数: 0

Abstract

As populations continue to age, interest in brain health is increasing. However, little is known about the relationship between health awareness and brain health in healthy adults. In this study, psychological questionnaire data from 184 participants were analyzed using multiple regression, with brain structural measures obtained by MRI as the dependent variables. Health awareness was positively associated with gray matter volume (GMV) in the whole brain, temporal lobe, and occipital lobe, after controlling for sex, age, education, and BMI. These associations remained significant after correction for multiple comparisons. Consistent with self-regulated learning (SRL) strategy theory, being health conscious may help individuals adopt and maintain behaviors that support brain health. To our knowledge, this is the first study to demonstrate a correlation between health awareness and brain structure in healthy adult men and women.

查看原文本刊更多论文

健康成人健康意识与全脑灰质体积相关

随着人口持续老龄化，人们对大脑健康的兴趣也在增加。然而，对于健康成年人的健康意识和大脑健康之间的关系，人们知之甚少。本研究对184名被试的心理问卷数据进行多元回归分析，以MRI获得的脑结构测量作为因变量。在控制性别、年龄、教育程度和BMI后，健康意识与全脑、颞叶和枕叶灰质体积（GMV）呈正相关。经过多次比较校正后，这些关联仍然显著。与自我调节学习（SRL）策略理论一致，健康意识可能有助于个体采取和维持有利于大脑健康的行为。据我们所知，这是首次证明健康成年男性和女性的健康意识与大脑结构之间存在相关性的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Brain Research Bulletin 医学-神经科学

CiteScore

6.90

自引率

2.60%

发文量

253

审稿时长

67 days

期刊介绍： The Brain Research Bulletin (BRB) aims to publish novel work that advances our knowledge of molecular and cellular mechanisms that underlie neural network properties associated with behavior, cognition and other brain functions during neurodevelopment and in the adult. Although clinical research is out of the Journal''s scope, the BRB also aims to publish translation research that provides insight into biological mechanisms and processes associated with neurodegeneration mechanisms, neurological diseases and neuropsychiatric disorders. The Journal is especially interested in research using novel methodologies, such as optogenetics, multielectrode array recordings and life imaging in wild-type and genetically-modified animal models, with the goal to advance our understanding of how neurons, glia and networks function in vivo.