Prevalence of digestive carriage of multi-drug resistant enterobacterales in hospitalized and community-based patients in Togo: a prospective study

IF 2.2 4区医学 Q2 INFECTIOUS DISEASES

Infectious diseases now Pub Date : 2025-09-10 DOI:10.1016/j.idnow.2025.105160

Rogatien Comlan Atoun , Iman Frédéric Youa , Lidaw Déassoua Bawe , Isidore Tchaou , Bodombossou Madera , Awereou Kotosso , Alexandre Bleibtreu , Taïssiri Adedjouma , André Pouwedeou Bedekelabou , Jules Tchédié , Yvette Siliadin , Eric Cardinale , Laurence Armand Lefevre , Brücker Gilles , Salou Mounerou , Claver Anoumou Dagnra , Didier Koumavi Ekouevi , Dominique Salmon

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Abstract

Introduction

The aim of this study was to estimate the prevalence of digestive tract carriage of ESBL-E/CPE among patients having consulted or been hospitalized in two university hospitals in Lomé in 2023.

Methods

A cross-sectional study was conducted from January to June 2023. Rectal swabs were collected from 230 participants (100 in maternity, 50 in pediatrics, 50 in trauma-orthopedics, and 30 in intensive care).

Results

Median age was four years for children and 30 years for adults. Overall prevalence of ESBL-E carriage was 59.6 %, while that of CPB was 6.1 %. Carriage was more frequent in hospital settings than in the community (64.6 % vs. 53.0 %). The main isolated species were Escherichia coli (95.6 %) and Klebsiella pneumoniae (27.7 %). Hospitalization units were associated with multidrug-resistant bacteria carriage.

Conclusion

These findings highlight a high prevalence of digestive tract carriage in hospital as well as community settings.

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多哥住院和社区患者消化道携带多重耐药肠杆菌的患病率：一项前瞻性研究。

前言：本研究的目的是估计2023年在lomoise两所大学医院就诊或住院的患者消化道携带ESBL-E/CPE的患病率。方法：于2023年1 - 6月进行横断面研究。收集230名参与者的直肠拭子（产科100名，儿科50名，创伤骨科50名，重症监护30名）。结果：儿童中位年龄为4岁，成人中位年龄为30 岁。ESBL-E携带的总患病率为59.6% %，而CPB为6.1 %。医院分娩比社区分娩更频繁（64.6 %对53.0 %）。主要分离种为大肠埃希菌（95.6% %）和肺炎克雷伯菌（27.7% %）。住院单位与多重耐药细菌携带相关。结论：这些发现突出了医院和社区环境中消化道运输的高患病率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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