{"title":"All systems go: CRISPR crosstalk for enhanced immunity.","authors":"Kalani Gast, Rodolphe Barrangou","doi":"10.1016/j.chom.2025.08.002","DOIUrl":null,"url":null,"abstract":"<p><p>In this issue of Cell Host & Microbe, companion manuscripts from Margolis & Meeske<sup>1</sup> and Smith & Fineran<sup>2</sup> demonstrate that CRISPR-Cas systems have an unprecedented level of cooperative crosstalk between different subtypes, which enables primed spacer acquisition. These studies illustrate how CRISPR-Cas systems cooperate to enhance adaptive immunity in bacteria.</p>","PeriodicalId":93926,"journal":{"name":"Cell host & microbe","volume":"33 9","pages":"1470-1472"},"PeriodicalIF":18.7000,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell host & microbe","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.chom.2025.08.002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
In this issue of Cell Host & Microbe, companion manuscripts from Margolis & Meeske1 and Smith & Fineran2 demonstrate that CRISPR-Cas systems have an unprecedented level of cooperative crosstalk between different subtypes, which enables primed spacer acquisition. These studies illustrate how CRISPR-Cas systems cooperate to enhance adaptive immunity in bacteria.
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