Effect of diverticulum entrance diameter on sigmoid sinus hemodynamics: a CFD and PIV experimental validation study.

IF 1.6 4区医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS

Computer Methods in Biomechanics and Biomedical Engineering Pub Date : 2025-09-10 DOI:10.1080/10255842.2025.2558048

Jincheng Liu, Suqin Huang, Zheng Hu, Feng Zhou, Xueran Ma, Bin Gao, Xiang Ding

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引用次数: 0

Abstract

Geometric changes in the sigmoid sinus diverticulum (SSD) can alter its hemodynamic - a primary factor contributing to pulsatile tinnitus (PT). However, not all SSD cases lead to clinical PT symptoms. This study aims to investigate the influence of the diameter of the diverticulum (EDD) on the hemodynamics of the sigmoid sinus in PT. We reconstructed CTA images from 26 PT patients. A statistical analysis of EDD, depth, and diverticulum angle, was conducted across these cases. Based on the geometric characteristics obtained, we established seven idealized models with varying EDDs and performed computational fluid dynamics simulations. Mass flow was set at the inlet, and the outlet was assigned zero pressure. We conducted Particle Image Velocimetry experiments verification. The SSD geometric models were 3D-printed using UV-curable resin material. As the EDD decreased from 11 mm to 9.65 mm, wall pressure within the SSD increased. However, further decreases in EDD from 9.65 mm to 8.3 mm resulted in a reduction in wall pressure (case1: 123.597 Pa vs. case2: 121.325 Pa vs. case3: 128.823 Pa vs. case4: 140.814 Pa vs. case5: 124.172 Pa vs. case6: 120.559 Pa vs. case7: 124.138 Pa). The pressure within the diverticulum first increased and then decreased, with the most intense vortex blood flow observed at an EDD of 9.65 mm. The EDD is a key factor influencing hemodynamic changes within the sigmoid sinus. The intermediate EDD induce more significant blood flow disturbances. This study provides theoretical insights for PT diagnosis and diverticulum morphology assessment.

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憩室入口直径对乙状窦血流动力学的影响：CFD和PIV实验验证研究。

乙状窦憩室（SSD）的几何变化可以改变其血流动力学，这是导致搏动性耳鸣（PT）的主要因素。然而，并非所有SSD病例都会导致临床PT症状。本研究旨在探讨憩室直径（EDD）对乙状窦血流动力学的影响。我们重建了26例PT患者的CTA图像。对这些病例的EDD、深度和憩室角度进行统计分析。基于得到的几何特性，建立了7种不同edd的理想模型，并进行了计算流体动力学仿真。入口设置质量流量，出口设置零压力。进行了粒子图像测速实验验证。采用uv固化树脂材料3d打印固态硬盘几何模型。随着EDD从11 mm减小到9.65 mm， SSD内壁面压力增大。然而，EDD从9.65 mm进一步降低到8.3 mm，导致壁压降低（cas1: 123.597 Pa, cas2: 121.325 Pa, cas3: 128.823 Pa, case4: 140.814 Pa, case5: 124.172 Pa, case6: 120.559 Pa, case7: 124.138 Pa）。憩室内压力先升高后降低，EDD为9.65 mm时旋涡血流最强。EDD是影响乙状窦血流动力学变化的关键因素。中间EDD诱导更明显的血流紊乱。本研究为PT诊断及憩室形态评估提供了理论依据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Computer Methods in Biomechanics and Biomedical Engineering 工程技术-工程：生物医学

CiteScore

4.10

自引率

6.20%

发文量

179

审稿时长

4-8 weeks

期刊介绍： The primary aims of Computer Methods in Biomechanics and Biomedical Engineering are to provide a means of communicating the advances being made in the areas of biomechanics and biomedical engineering and to stimulate interest in the continually emerging computer based technologies which are being applied in these multidisciplinary subjects. Computer Methods in Biomechanics and Biomedical Engineering will also provide a focus for the importance of integrating the disciplines of engineering with medical technology and clinical expertise. Such integration will have a major impact on health care in the future.