Comprehensive study on selenium- and zinc-enriched duck embryo egg powder: component analysis, safety evaluation and prostate protection effect.

IF 3.5 2区农林科学 Q1 AGRICULTURE, MULTIDISCIPLINARY

Journal of the Science of Food and Agriculture Pub Date : 2025-09-08 DOI:10.1002/jsfa.70169

Pengkui Xia, Ruyang Wang, Dandan Ruan, Tao Hou

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Abstract

Background: Selenium and zinc elements have been proven to participate in immune regulation and infertility improvement. Their potential has been confirmed in in prostatitis and reproductive performance modulation. In this study, first the composition of selenium- and zinc-enriched duck embryo egg (SZDE) powder was analyzed, especially trace elements and oligopeptides. Secondly, acute toxicity was evaluated. A prostatitis rat model was constructed to explore the SZDE anti-inflammation effects.

Results: Levels of selenium and zinc elements were much higher in SZDE than in normal eggs. SZDE showed no toxicity in male or female mice according to behavior and pathological parameters. Significant downregulated pro-inflammatory cytokines and increased androgens levels (P < 0.05) were found after the SZDE intervention. Prostatitis was significantly improved via inhibition of the MAPK/p38 pathway following SZDE treatment (P < 0.05).

Conclusion: Overall, these findings demonstrated the security and prostatitis regulation effect of SZDE, indicating that it might serve as a new dietary strategy for prostate health. © 2025 Society of Chemical Industry.

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富硒、锌鸭胚蛋粉的综合研究：成分分析、安全性评价及前列腺保护作用。

背景：硒和锌元素已被证实参与免疫调节和改善不孕症。它们在前列腺炎和生殖功能调节方面的潜力已得到证实。本研究首先对富硒、富锌鸭胚蛋（SZDE）粉的成分进行了分析，重点分析了其微量元素和寡肽。其次，进行急性毒性评价。建立前列腺炎大鼠模型，探讨SZDE的抗炎作用。结果：SZDE中硒、锌元素含量明显高于正常鸡蛋。从行为和病理指标看，SZDE对雌雄小鼠均无毒性。结论：综上所述，SZDE具有安全性和前列腺炎调节作用，可能作为一种新的前列腺健康饮食策略。©2025化学工业协会。

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来源期刊

Journal of the Science of Food and Agriculture 工程技术-农业综合

CiteScore

8.10

自引率

4.90%

发文量

634

审稿时长

3.1 months

期刊介绍： The Journal of the Science of Food and Agriculture publishes peer-reviewed original research, reviews, mini-reviews, perspectives and spotlights in these areas, with particular emphasis on interdisciplinary studies at the agriculture/ food interface. Published for SCI by John Wiley & Sons Ltd. SCI (Society of Chemical Industry) is a unique international forum where science meets business on independent, impartial ground. Anyone can join and current Members include consumers, business people, environmentalists, industrialists, farmers, and researchers. The Society offers a chance to share information between sectors as diverse as food and agriculture, pharmaceuticals, biotechnology, materials, chemicals, environmental science and safety. As well as organising educational events, SCI awards a number of prestigious honours and scholarships each year, publishes peer-reviewed journals, and provides Members with news from their sectors in the respected magazine, Chemistry & Industry . Originally established in London in 1881 and in New York in 1894, SCI is a registered charity with Members in over 70 countries.