{"title":"A Multifaceted Review on Neodiosmin In Planta Distribution, (Bio)synthesis, Food and Health Effects","authors":"Yuxuan Zhao, Jingyimei Liang, Xincheng Wu, Mohamed A. Farag, Predrag Putnik","doi":"10.1002/fpf2.70016","DOIUrl":null,"url":null,"abstract":"<p>Neodiosmin (NEO) is a major glycosylated flavone that is derived from the bitter flavanone neo-hesperidin in citrus fruits including orange, lime, and lemon. One of the most important features of NEO is that it exerts a notable debittering effect on plant flavonoids justifying its wide use as a food additive. NEO upregulates plants' defense and immunity, aside from its several health benefits in humans including anti-inflammatory, antioxidant, anti-diabetic, lipid-lowering, antibacterial, and anti-cancer. NEO presented development potential and application prospects in various fields warranting more studies on this flavonoid. This review delves into the occurrence, and biosynthetic pathways of NEO, highlighting the needed future research to maximize its application in medicine, food, and agriculture.</p>","PeriodicalId":100565,"journal":{"name":"Future Postharvest and Food","volume":"2 3","pages":"237-247"},"PeriodicalIF":0.0000,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://iadns.onlinelibrary.wiley.com/doi/epdf/10.1002/fpf2.70016","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future Postharvest and Food","FirstCategoryId":"1085","ListUrlMain":"https://iadns.onlinelibrary.wiley.com/doi/10.1002/fpf2.70016","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Neodiosmin (NEO) is a major glycosylated flavone that is derived from the bitter flavanone neo-hesperidin in citrus fruits including orange, lime, and lemon. One of the most important features of NEO is that it exerts a notable debittering effect on plant flavonoids justifying its wide use as a food additive. NEO upregulates plants' defense and immunity, aside from its several health benefits in humans including anti-inflammatory, antioxidant, anti-diabetic, lipid-lowering, antibacterial, and anti-cancer. NEO presented development potential and application prospects in various fields warranting more studies on this flavonoid. This review delves into the occurrence, and biosynthetic pathways of NEO, highlighting the needed future research to maximize its application in medicine, food, and agriculture.
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