[Validation Study on the Developed Method for Cyanide in Various Mineral Waters].

IF 0.2 4区农林科学 Q4 FOOD SCIENCE & TECHNOLOGY

Food Hygiene and Safety Science Pub Date : 2025-01-01 DOI:10.3358/shokueishi.66.46

Hiroshi Sakuragi, Masako Suzuki, Hiroyuki Ohno

{"title":"[Validation Study on the Developed Method for Cyanide in Various Mineral Waters].","authors":"Hiroshi Sakuragi, Masako Suzuki, Hiroyuki Ohno","doi":"10.3358/shokueishi.66.46","DOIUrl":null,"url":null,"abstract":"<p><p>A method for the determination of two kinds of cyanide, namely cyanide ion and cyanogen chloride, in various mineral waters (MWs) has been developed and validated. MWs are varying in the degree of hardness and carbonation. The results of two carbonated MWs obtained through the validated official method for cyanide analysis in tap water did not meet the criteria of the validation guideline for MW in Japan. Furthermore, in the pH adjustment during pretreatment, some MWs did not reach approximately pH 2.4, the level assumed in tap water quality tests. After five-fold dilution of the samples with phosphate buffer, the specified pH value of 2.4 was achieved, leading to the improvements in trueness. The validation tests of the method with the additional dilution step showed the trueness from 93.0 to 103.8%, RSDs of repeatability and within-laboratory reproducibility below 3.83% and 4.68%, respectively. These values fulfill the criteria on both analytes. The developed method indicated the potential applicability for accurate determination of cyanide ion and cyanogen chloride in a range of commercially available MW products.</p>","PeriodicalId":54373,"journal":{"name":"Food Hygiene and Safety Science","volume":"66 3","pages":"46-50"},"PeriodicalIF":0.2000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food Hygiene and Safety Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.3358/shokueishi.66.46","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

A method for the determination of two kinds of cyanide, namely cyanide ion and cyanogen chloride, in various mineral waters (MWs) has been developed and validated. MWs are varying in the degree of hardness and carbonation. The results of two carbonated MWs obtained through the validated official method for cyanide analysis in tap water did not meet the criteria of the validation guideline for MW in Japan. Furthermore, in the pH adjustment during pretreatment, some MWs did not reach approximately pH 2.4, the level assumed in tap water quality tests. After five-fold dilution of the samples with phosphate buffer, the specified pH value of 2.4 was achieved, leading to the improvements in trueness. The validation tests of the method with the additional dilution step showed the trueness from 93.0 to 103.8%, RSDs of repeatability and within-laboratory reproducibility below 3.83% and 4.68%, respectively. These values fulfill the criteria on both analytes. The developed method indicated the potential applicability for accurate determination of cyanide ion and cyanogen chloride in a range of commercially available MW products.

查看原文本刊更多论文

[各种矿泉水中氰化物测定方法的验证研究]。

建立了一种测定各种矿泉水中氰化物离子和氯氰的方法，并进行了验证。MWs的硬度和碳化程度各不相同。通过自来水中氰化物分析的官方验证方法获得的两种碳化MWs的结果不符合日本MWs验证指南的标准。此外，在预处理过程中的pH调节中，一些MWs没有达到自来水水质测试中假设的pH值2.4左右。磷酸盐缓冲液将样品稀释5倍后，达到规定pH值2.4，从而提高了正确率。加稀释步骤的验证结果表明，该方法的准确度为93.0 ~ 103.8%，重复性rsd < 3.83%，实验室内重复性rsd < 4.68%。这些值满足两种分析物的标准。所建立的方法表明，该方法可能适用于准确测定一系列市售MW产品中的氰化物离子和氯化氰。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊