Chronic overlapping pain conditions in individuals with active opioid use disorder: a descriptive study of syringe program participants.

IF 1.1 4区 医学 Q3 SUBSTANCE ABUSE
Johnathan Rausch, Steven E Harte, David A Williams, Daniel J Clauw, Megan Deaner, Leon Brodsky, Jace Floyd, Orman Trent Hall
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Abstract

Background: Comorbidity between opioid use disorder (OUD) and chronic pain is substantial. Pain has been shown to be a motivator for OUD onset, maintenance, relapse, and treatment delay. A cluster of pain conditions known as chronic overlapping pain conditions (COPCs), also now referred to in contemporary ICD classification as primary pain conditions, are particularly refractory to traditional forms of pain treatment, and likely adversely impact comorbid OUD.

Objective: This cross-sectional descriptive study sought to obtain a better understanding of the prevalence of COPCs among individuals with OUD.

Methods: The COPCs screener was originally developed to address the challenges of readily assessing for multiple of these conditions; which is important given that the number of said conditions acts as a marker for the likely presence of nociplastic pain. This screener was used alongside supplementary survey items to describe COPCs and pain distribution in a sample of individuals with active OUD recruited from a syringe exchange program.

Results: Comparisons of COPC prevalence between the study sample and global prevalence estimates found that among those with OUD, there is a significantly higher-than-expected prevalence of chronic low back pain, myalgic encephalomyelitis/chronic fatigue syndrome, chronic migraine headache, and fibromyalgia.

Conclusions: Results support further investigations into COPCs in the context of OUD. Further research may reveal methods of enhancing OUD treatment and identifying additional targets for intervention and prevention.

活动性阿片类药物使用障碍个体的慢性重叠疼痛状况:注射器计划参与者的描述性研究。
背景:阿片类药物使用障碍(OUD)和慢性疼痛之间的共病是实质性的。疼痛已被证明是OUD发作、维持、复发和治疗延迟的诱因。一组疼痛状况被称为慢性重叠疼痛状况(COPCs),在当代ICD分类中也被称为原发性疼痛状况,对传统形式的疼痛治疗尤其难治,并可能对合并症OUD产生不利影响。目的:本横断面描述性研究旨在更好地了解OUD患者中COPCs的患病率。方法:最初开发COPCs筛选器是为了解决容易评估多种这些条件的挑战;这一点很重要,因为上述情况的数量可以作为可能存在伤害性疼痛的标志。该筛选器与补充调查项目一起用于描述从注射器交换计划中招募的活动性OUD患者样本中的COPCs和疼痛分布。结果:比较研究样本与全球患病率估计之间的COPC患病率发现,在OUD患者中,慢性腰痛、肌痛性脑脊髓炎/慢性疲劳综合征、慢性偏头痛和纤维肌痛的患病率明显高于预期。结论:结果支持在OUD背景下进一步研究COPCs。进一步的研究可能会揭示加强OUD治疗的方法,并确定干预和预防的额外目标。
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来源期刊
CiteScore
4.30
自引率
4.30%
发文量
69
期刊介绍: The Journal of Addictive Diseases is an essential, comprehensive resource covering the full range of addictions for today"s addiction professional. This in-depth, practical journal helps you stay on top of the vital issues and the clinical skills necessary to ensure effective practice. The latest research, treatments, and public policy issues in addiction medicine are presented in a fully integrated, multi-specialty perspective. Top researchers and respected leaders in addiction issues share their knowledge and insights to keep you up-to-date on the most important research and practical applications.
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