Neurodevelopmental Outcomes of Mycotoxins Exposure and Effect on Brain Development in Infants and Young Children

IF 2.3 4区医学 Q2 DEVELOPMENTAL BIOLOGY

Developmental Neurobiology Pub Date : 2025-09-02 DOI:10.1002/dneu.23000

Laure Viviane Ndam Ngoungoure, Wilfred Angie Abia, Brice Vincent Ayissi Owona, Yacouba Foupouapouognigni, Ferdinand Kouoh Elombo, Herman Philipe Njitoyap Nfombouot, Epole Ngolle Ntungwe, Frederic N. Njayou, Angéle N. Tchana, Paul F. Moundipa

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引用次数: 0

Abstract

This comprehensive literature review was conducted to identify relevant studies on mycotoxins and brain development in children. Existing studies suggest that mycotoxin exposure during critical periods of brain development may lead to neurocognitive impairments in children. Some studies have reported associations between mycotoxin exposure and reduced cognitive abilities, impaired motor skills, and behavioral problems. Additionally, mycotoxins have been shown to disrupt neural signaling pathways and interfere with neurotransmitter function, potentially contributing to neurodevelopmental disorders. This comprehensive review has provided a comprehensive overview of the possible evidence on the association between mycotoxin exposure and brain development in children and identified areas for future research.

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霉菌毒素暴露对婴幼儿大脑发育的影响及神经发育结局

本文对真菌毒素与儿童大脑发育的相关研究进行了全面的文献综述。现有的研究表明，在大脑发育的关键时期接触真菌毒素可能导致儿童神经认知障碍。一些研究报告了霉菌毒素暴露与认知能力下降、运动技能受损和行为问题之间的关联。此外，真菌毒素已被证明可破坏神经信号通路并干扰神经递质功能，可能导致神经发育障碍。这一综合综述全面概述了霉菌毒素暴露与儿童大脑发育之间关系的可能证据，并确定了未来研究的领域。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Developmental Neurobiology 生物-发育生物学

CiteScore

6.50

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： Developmental Neurobiology (previously the Journal of Neurobiology ) publishes original research articles on development, regeneration, repair and plasticity of the nervous system and on the ontogeny of behavior. High quality contributions in these areas are solicited, with an emphasis on experimental as opposed to purely descriptive work. The Journal also will consider manuscripts reporting novel approaches and techniques for the study of the development of the nervous system as well as occasional special issues on topics of significant current interest. We welcome suggestions on possible topics from our readers.