{"title":"Antibacterial activity and wound healing promotion of biomass carbon dots derived from a forestry pest, Glenea cantor (Coleoptera: Cerambycidae)","authors":"Gang Ren, Wen Zhang, Yuan Tang, Bangyu Zhong, Liangshan Ming, Qimeng Fan, Jia Huang, Hongning Liu, Zhixin Li, Ping Luo, Zishu Dong","doi":"10.1186/s40538-025-00848-1","DOIUrl":null,"url":null,"abstract":"<div><p>Forestry pests pose serious ecological challenges, yet their biological value remains underexplored. This study aimed to convert the destructive longhorn beetle <i>Glenea cantor</i> (<i>G. cantor</i>) into biomass carbon dots (GC-CDs) with both antibacterial and wound healing properties. GC-CDs were synthesized by a simple microwave-assisted method and characterized by techniques such as transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS). The particles were quasi-spherical with an average size of 1.02 nm and displayed excellent water solubility. In vitro assays confirmed the low cytotoxicity and hemolysis rates of GC-CDs, while in vivo evaluations showed no systemic toxicity. GC-CDs inhibited <i>Escherichia coli</i> growth and enhanced cell migration and wound closure in scratch assays, Transwell tests, and mouse wound models. These results demonstrate that GC-CDs possess dual antibacterial and wound healing activities, offering a sustainable strategy for transforming forestry pests into valuable biomedical resources.</p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":512,"journal":{"name":"Chemical and Biological Technologies in Agriculture","volume":"12 1","pages":""},"PeriodicalIF":5.2000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chembioagro.springeropen.com/counter/pdf/10.1186/s40538-025-00848-1","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical and Biological Technologies in Agriculture","FirstCategoryId":"97","ListUrlMain":"https://link.springer.com/article/10.1186/s40538-025-00848-1","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"AGRICULTURE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Forestry pests pose serious ecological challenges, yet their biological value remains underexplored. This study aimed to convert the destructive longhorn beetle Glenea cantor (G. cantor) into biomass carbon dots (GC-CDs) with both antibacterial and wound healing properties. GC-CDs were synthesized by a simple microwave-assisted method and characterized by techniques such as transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS). The particles were quasi-spherical with an average size of 1.02 nm and displayed excellent water solubility. In vitro assays confirmed the low cytotoxicity and hemolysis rates of GC-CDs, while in vivo evaluations showed no systemic toxicity. GC-CDs inhibited Escherichia coli growth and enhanced cell migration and wound closure in scratch assays, Transwell tests, and mouse wound models. These results demonstrate that GC-CDs possess dual antibacterial and wound healing activities, offering a sustainable strategy for transforming forestry pests into valuable biomedical resources.
林业害虫对生态环境构成严重挑战，但其生物学价值尚未得到充分发掘。本研究旨在将具有破坏性的长角甲虫Glenea cantor （G. cantor）转化为具有抗菌和伤口愈合性能的生物质碳点（GC-CDs）。采用简单的微波辅助法合成了GC-CDs，并利用透射电子显微镜（TEM）、傅里叶变换红外光谱（FTIR）和x射线光电子能谱（XPS）等技术对其进行了表征。颗粒呈准球形，平均粒径为1.02 nm，具有良好的水溶性。体外实验证实GC-CDs具有较低的细胞毒性和溶血率，而体内实验显示其无全身毒性。在抓痕试验、Transwell试验和小鼠伤口模型中，GC-CDs抑制大肠杆菌生长，增强细胞迁移和伤口愈合。这些结果表明，GC-CDs具有双重抗菌和伤口愈合活性，为将林业害虫转化为有价值的生物医学资源提供了可持续的策略。图形抽象
期刊介绍：
Chemical and Biological Technologies in Agriculture is an international, interdisciplinary, peer-reviewed forum for the advancement and application to all fields of agriculture of modern chemical, biochemical and molecular technologies. The scope of this journal includes chemical and biochemical processes aimed to increase sustainable agricultural and food production, the evaluation of quality and origin of raw primary products and their transformation into foods and chemicals, as well as environmental monitoring and remediation. Of special interest are the effects of chemical and biochemical technologies, also at the nano and supramolecular scale, on the relationships between soil, plants, microorganisms and their environment, with the help of modern bioinformatics. Another special focus is the use of modern bioorganic and biological chemistry to develop new technologies for plant nutrition and bio-stimulation, advancement of biorefineries from biomasses, safe and traceable food products, carbon storage in soil and plants and restoration of contaminated soils to agriculture.
This journal presents the first opportunity to bring together researchers from a wide number of disciplines within the agricultural chemical and biological sciences, from both industry and academia. The principle aim of Chemical and Biological Technologies in Agriculture is to allow the exchange of the most advanced chemical and biochemical knowledge to develop technologies which address one of the most pressing challenges of our times - sustaining a growing world population.
Chemical and Biological Technologies in Agriculture publishes original research articles, short letters and invited reviews. Articles from scientists in industry, academia as well as private research institutes, non-governmental and environmental organizations are encouraged.
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