Risk factors for hospital admission and length of stay for children with and without congenital anomalies: a EUROlinkCAT cohort study.

IF 2.3 4区 医学 Q2 PEDIATRICS
Joanne Given, Ester Garne, Joan K Morris, Silvia Baldacci, Elisa Ballardini, Mika Gissler, Francesca Gorini, Sonja Kiuru-Kuhlefelt, Stine Kjaer Urhoj, Marco Manfrini, Joachim Tan, Maria Loane
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Abstract

Objective: To evaluate risk factors for hospital admission and length of stay (LOS) among children with and without congenital anomalies (CAs).

Design: A population-based linkage cohort study including 50 353 children with major CAs and 1 259 925 children without CAs from four EUROCAT registry areas in three countries. Data on children born 1995-2014 were linked to hospital discharge databases 1995-2015. HRs and incidence rate ratios estimated risk of admission and LOS for children aged <1 and 1-4 years by birth cohort, gestational age, sex, maternal age, multiple births and maternal education. Estimates were pooled using random effects meta-analysis.

Results: In children <1 year, twins/triplets with CAs were 34% more likely to be admitted and had over two times the LOS compared with singletons, while twins/triplets without CAs were over two and a half times as likely to be admitted and had six times longer stays. Despite this, a higher proportion of twins/triplets with CAs were admitted compared to those without CAs (91% vs 65%) and had longer LOS (20 days vs 10). Smaller increases in risk of admission or LOS were found in boys, young mothers and low maternal education. Preterm birth was a major risk factor for admission and LOS.

Conclusions: While the impact of risk factors on hospital admission and LOS was generally greater in children without CAs, a higher proportion of children with CAs were admitted and had longer stays. These findings have implications for health care planning and for counselling parents regarding their child's future healthcare needs.

有或无先天性畸形儿童住院和住院时间的危险因素:一项EUROlinkCAT队列研究
目的:评价有和无先天性异常儿童住院和住院时间(LOS)的危险因素。设计:一项基于人群的连锁队列研究,包括来自3个国家的4个EUROCAT登记区域的50353名患有严重ca的儿童和1 259 925名无ca的儿童。1995-2014年出生的儿童的数据与1995-2015年的医院出院数据库相关联。hr和发病率比值估计了老年儿童的住院和LOS风险结果:在儿童中结论:虽然危险因素对住院和LOS的影响通常在没有ca的儿童中更大,但有ca的儿童住院的比例更高,住院时间更长。这些发现对卫生保健计划和就孩子未来的卫生保健需求向父母提供咨询具有启示意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMJ Paediatrics Open
BMJ Paediatrics Open Medicine-Pediatrics, Perinatology and Child Health
CiteScore
4.10
自引率
3.80%
发文量
124
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