Sarcosine shows promise in preventing sarcopenia

Abstract

Metabolomics and lipidomics uncover the metabolic features and heterogeneity associated with sarcopenia — the age-related loss of muscle mass and strength. Circulating sarcosine levels decrease in sarcopenia and supplementation with sarcosine enhances fat metabolism and muscle repair in mice by activating anti-inflammatory macrophages. These results suggest sarcosine could be used therapeutically to slow sarcopenic progression.