Personalizing transcranial electrical stimulation.

IF 15.1 1区 医学 Q1 NEUROSCIENCES
Trends in Neurosciences Pub Date : 2025-09-01 Epub Date: 2025-08-07 DOI:10.1016/j.tins.2025.07.007
Sybren Van Hoornweder, Charlotte J Stagg, Miles Wischnewski
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引用次数: 0

Abstract

Transcranial electrical stimulation (tES) encompasses non-invasive neuromodulation techniques, such as transcranial direct and alternating current stimulation, which modulate the central nervous system to probe causal links between the brain and behavior and treat disorders. Unfortunately, fixed stimulation paradigms induce variable effects due to intra- and interindividual factors. Consequently, personalized approaches to tES are increasingly used. In this review, we highlight this emerging domain of human brain stimulation, examining strategies for the personalization of stimulation parameters and their underlying rationales. Multiparameter personalization and the identification of markers indicating tES efficacy represent promising directions. Personalization is not a panacea for all the challenges of tES, but marks an essential step toward reducing the variability of this technique.

个性化经颅电刺激。
经颅电刺激(tES)包括非侵入性神经调节技术,如经颅直流电刺激和交流电刺激,通过调节中枢神经系统来探索大脑和行为之间的因果关系并治疗疾病。不幸的是,由于个体内部和个体之间的因素,固定的刺激范式会引起不同的影响。因此,越来越多地使用个性化的tES方法。在这篇综述中,我们强调了这一新兴的人类大脑刺激领域,研究了刺激参数个性化的策略及其潜在的原理。多参数个性化和识别表明tES疗效的标记物是有希望的方向。个性化并不是解决te所有挑战的灵丹妙药,但它标志着减少这种技术可变性的重要一步。
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来源期刊
Trends in Neurosciences
Trends in Neurosciences 医学-神经科学
CiteScore
26.50
自引率
1.30%
发文量
123
审稿时长
6-12 weeks
期刊介绍: For over four decades, Trends in Neurosciences (TINS) has been a prominent source of inspiring reviews and commentaries across all disciplines of neuroscience. TINS is a monthly, peer-reviewed journal, and its articles are curated by the Editor and authored by leading researchers in their respective fields. The journal communicates exciting advances in brain research, serves as a voice for the global neuroscience community, and highlights the contribution of neuroscientific research to medicine and society.
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