Efficacy of a feed additive consisting of 6-phytase produced by (Komagataella phaffii CGMCC 7.370) (VTR-phytase) for all pigs and growing poultry species (Victory Enzymes GmbH)

IF 3.3 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López-Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto-Maradona, Ilen Röhe, Katerina Theodoridou, Montserrat Anguita, Matteo L. Innocenti, Marianna Kujawa, Jordi Ortuño
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引用次数: 0

Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the efficacy of 6-phytase produced by Komagataella phaffii CGMCC 7.370 (VTR-phytase) as a zootechnical feed additive for all pigs and growing poultry species. The additive is intended to be commercialised in two formulations: liquid and powder. In a previous opinion the FEEDAP Panel concluded that the additive is safe for target species, consumers and environment. The FEEDAP Panel deemed that both formulations of the additive are not skin and eyes irritant but should be considered skin and respiratory sensitisers. The FEEDAP Panel concluded that VTR-phytase has potential to be efficacious in laying hens at 1000 U phytase/kg complete feed, and this conclusion was extended to all laying and reproductive poultry. However, due to the lack of sufficient data, the Panel was not in a position to conclude on the efficacy for poultry for fattening or reared for laying/breeding, and in any porcine species. The applicant provided new trials to support the efficacy of the additive on those target species. Based on the data provided in the previous and current application, the Panel concluded that the additive has a potential to be efficacious as a zootechnical additive for all poultry for fattening and reared for laying/breeding and reproductive porcine species at 500 U phytase/kg complete feed and all porcine species for fattening and reared for reproduction at 750 U phytase/kg complete feed.

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由(Komagataella phaffii CGMCC 7.370)生产的6-植酸酶(vtr -植酸酶)组成的饲料添加剂对所有猪和生长家禽品种的效果(Victory enzyme GmbH)
根据欧盟委员会的要求,欧洲食品安全局被要求就Komagataella phaffii CGMCC 7.370生产的6-植酸酶(VTR-phytase)作为所有猪和生长家禽的动物技术饲料添加剂的功效发表科学意见。该添加剂打算以两种配方商业化:液体和粉末。在之前的意见中,FEEDAP小组得出结论,该添加剂对目标物种、消费者和环境都是安全的。FEEDAP小组认为,添加剂的两种配方对皮肤和眼睛没有刺激性,但应被视为皮肤和呼吸道致敏物。FEEDAP小组得出结论,在1000 U植酸酶/kg全料饲料中,vrr -植酸酶有可能对蛋鸡有效,并将这一结论推广到所有蛋鸡和繁殖家禽。然而,由于缺乏足够的数据,小组无法就该药物对育肥家禽或饲养用于产蛋/繁殖的家禽以及任何猪种的功效得出结论。申请人提供了新的试验,以支持添加剂对这些目标物种的功效。根据以前和目前申请中提供的数据,评估小组得出结论,该添加剂有潜力作为一种动物技术添加剂,适用于所有育肥家禽和产蛋猪/种猪和繁殖猪品种,使用500 U植酸酶/公斤全饲料,适用于所有育肥和繁殖猪品种,使用750 U植酸酶/公斤全饲料。
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来源期刊
EFSA Journal
EFSA Journal Veterinary-Veterinary (miscellaneous)
CiteScore
5.20
自引率
21.20%
发文量
422
审稿时长
5 weeks
期刊介绍: The EFSA Journal covers methods of risk assessment, reports on data collected, and risk assessments in the individual areas of plant health, plant protection products and their residues, genetically modified organisms, additives and products or substances used in animal feed, animal health and welfare, biological hazards including BSE/TSE, contaminants in the food chain, food contact materials, enzymes, flavourings and processing aids, food additives and nutrient sources added to food, dietetic products, nutrition and allergies.
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