Preexposure prophylaxis initiation and alcohol-related sexual risk among young men who have sex with men.

IF 3.2 2区 心理学 Q1 PSYCHOLOGY
Emma R Hayden, Robert D Dvorak, Anthony Bamonte, Xiang Cai, Martin J Downing, Ellen Benoit, Eric W Schrimshaw
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引用次数: 0

Abstract

Objective: Human immunodeficiency virus (HIV) infection is a significant public health concern, particularly among young men who have sex with men (YMSM). Preexposure prophylaxis (PrEP) is highly effective in preventing HIV infection. However, PrEP does not protect against other sexually transmitted infections. Previous studies have shown unintended consequences following PrEP initiation, including increased sexual risk behaviors. Problematic alcohol use, to which YMSM are particularly vulnerable, may also play a role in increasing sexual risk. The present study examines the prospective relationship between PrEP initiation and alcohol-related sexual behaviors among YMSM.

Method: One hundred thirty-nine YMSM (Mage = 21.22) were enrolled in a longitudinal study examining PrEP initiation and alcohol-related sexual risk over 18 months. Participants completed a baseline assessment and follow-up assessments every 6 months. Data collection took place between 2016 and 2020.

Results: PrEP initiation was modeled at Time 1, Time 2, Time 3, and Time 4. Alcohol-related sexual risk behaviors were measured at Time 1 and Time 4. The trajectory of PrEP initiation was used to predict latent change in alcohol-related sexual behaviors. Consistent with our hypothesis, a combined latent change score and latent trajectory model revealed a positive association between PrEP initiation and alcohol-related sexual behaviors between baseline and 18-month follow-up.

Conclusion: These results are consistent with research identifying a potentially high-risk period following PrEP initiation among a vulnerable group (YMSM), with implications for risk assessment and interventions targeting alcohol-related sexual behaviors among YMSM. Findings may aid in reducing adverse sexual outcomes among YMSM who initiate PrEP and ultimately contribute to the minimization of sexual health disparities among YMSM. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

年轻男男性行为者暴露前预防开始和酒精相关的性风险
目的:人类免疫缺陷病毒(HIV)感染是一个重大的公共卫生问题,特别是在男男性行为的年轻男子中。暴露前预防(PrEP)在预防艾滋病毒感染方面非常有效。然而,PrEP并不能预防其他性传播感染。先前的研究显示了PrEP开始后的意想不到的后果,包括性风险行为的增加。有问题的酒精使用,这是年轻男性特别容易受到伤害的,也可能在增加性风险方面发挥作用。本研究探讨了PrEP开始与YMSM中与酒精相关的性行为之间的潜在关系。方法:139名YMSM(年龄21.22)被纳入一项为期18个月的纵向研究,研究PrEP开始和酒精相关的性风险。参与者每6个月完成一次基线评估和随访评估。数据收集于2016年至2020年期间进行。结果:在时间1、时间2、时间3和时间4建立PrEP启动模型。在时间1和时间4测量与酒精相关的性风险行为。PrEP开始的轨迹被用来预测酒精相关性行为的潜在变化。与我们的假设一致,综合潜在变化评分和潜在轨迹模型显示,在基线和18个月的随访期间,PrEP开始与酒精相关的性行为之间存在正相关。结论:这些结果与一项研究一致,该研究确定了弱势群体(YMSM)开始PrEP后的潜在高危期,这对YMSM中与酒精相关的性行为的风险评估和干预具有重要意义。研究结果可能有助于减少开始PrEP的年轻男性的不良性结局,并最终有助于减少年轻男性之间的性健康差异。(PsycInfo Database Record (c) 2025 APA,版权所有)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Health Psychology
Health Psychology 医学-心理学
CiteScore
4.90
自引率
2.40%
发文量
170
审稿时长
4-8 weeks
期刊介绍: Health Psychology publishes articles on psychological, biobehavioral, social, and environmental factors in physical health and medical illness, and other issues in health psychology.
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