Green fabrication of diazo-coupled porous polymer as solid-phase extraction adsorbent coupled with HPLC-MS for sensitive detection of phenolic endocrine disruptors in pork and carp

IF 9.8 1区农林科学 Q1 CHEMISTRY, APPLIED

Food Chemistry Pub Date : 2025-07-25 DOI:10.1016/j.foodchem.2025.145682

Ziqi Xu , Xiaocui Chen , Zhi Li , Qianqian Wang , Chun Wang , Qiuhua Wu

{"title":"Green fabrication of diazo-coupled porous polymer as solid-phase extraction adsorbent coupled with HPLC-MS for sensitive detection of phenolic endocrine disruptors in pork and carp","authors":"Ziqi Xu , Xiaocui Chen , Zhi Li , Qianqian Wang , Chun Wang , Qiuhua Wu","doi":"10.1016/j.foodchem.2025.145682","DOIUrl":null,"url":null,"abstract":"<div><div>The development of highly practical method for the monitoring of environmental endocrine disruptor (EDCs) is of vital importance. Herein, a nitrogen-rich porous organic polymer (DT-POP1) bearing phenolic -OH groups was synthesized by green coupling reaction between diosmetin and N,N,N′,N′-tetra(<em>p</em>-aminophenyl)-<em>p</em>-phenylenediamine. The DT-POP1 was used as solid-phase extraction (SPE) adsorbent, exhibiting brilliant extraction performance for five phenolic EDCs (bisphenol S, bisphenol F, bisphenol A, bisphenol B, and 4-tert-butylphenol). Coupling DT-POP1 based SPE with liquid chromatography-mass spectrometry, a highly sensitive and reliable method for detecting trace phenolic EDCs in pork and carp samples was developed. The detection limits of this method for pork and carp were 1.2–1.9 ng g<sup>−1</sup> and 1.2–2.1 ng g<sup>−1</sup>, respectively. The recovery of spiked samples was 84.1–104 %, and the relative standard deviation was 2.9–6.5 %. This study offers a viable strategy for trace-level analysis of EDCs in food, also highlighting the green preparation of diazo-coupled porous materials as fabulous adsorbent for practical applications.</div></div>","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"493 ","pages":"Article 145682"},"PeriodicalIF":9.8000,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food Chemistry","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0308814625029334","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}

引用次数: 0

Abstract

The development of highly practical method for the monitoring of environmental endocrine disruptor (EDCs) is of vital importance. Herein, a nitrogen-rich porous organic polymer (DT-POP1) bearing phenolic -OH groups was synthesized by green coupling reaction between diosmetin and N,N,N′,N′-tetra(p-aminophenyl)-p-phenylenediamine. The DT-POP1 was used as solid-phase extraction (SPE) adsorbent, exhibiting brilliant extraction performance for five phenolic EDCs (bisphenol S, bisphenol F, bisphenol A, bisphenol B, and 4-tert-butylphenol). Coupling DT-POP1 based SPE with liquid chromatography-mass spectrometry, a highly sensitive and reliable method for detecting trace phenolic EDCs in pork and carp samples was developed. The detection limits of this method for pork and carp were 1.2–1.9 ng g⁻¹ and 1.2–2.1 ng g⁻¹, respectively. The recovery of spiked samples was 84.1–104 %, and the relative standard deviation was 2.9–6.5 %. This study offers a viable strategy for trace-level analysis of EDCs in food, also highlighting the green preparation of diazo-coupled porous materials as fabulous adsorbent for practical applications.

Abstract Image

查看原文本刊更多论文

绿色制备重氮偶联多孔聚合物固相萃取吸附剂结合高效液相色谱-质谱联用检测猪肉和鲤鱼中酚类内分泌干扰物

开发高度实用的环境内分泌干扰物监测方法具有重要意义。本文通过硅油素与N，N,N′，N′-四（对氨基苯基）-对苯二胺的绿色偶联反应，合成了含酚-OH基团的富氮多孔有机聚合物（DT-POP1）。采用DT-POP1作为固相萃取（SPE）吸附剂，对5种酚类EDCs（双酚S、双酚F、双酚A、双酚B和4-叔丁基酚）均有较好的萃取效果。建立了基于DT-POP1的固相萃取与液相色谱-质谱联用检测猪肉和鲤鱼样品中痕量酚类EDCs的高灵敏度、高可靠性方法。猪肉和鲤鱼的检出限分别为1.2 ~ 1.9 ng g−1和1.2 ~ 2.1 ng g−1。加样回收率为84.1 ~ 104 %，相对标准偏差为2.9 ~ 6.5 %。本研究为食品中EDCs的痕量分析提供了一种可行的策略，同时也突出了重氮偶联多孔材料的绿色制备作为一种极好的吸附剂的实际应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Food Chemistry 工程技术-食品科技

CiteScore

16.30

自引率

10.20%

发文量

3130

审稿时长

122 days

期刊介绍： Food Chemistry publishes original research papers dealing with the advancement of the chemistry and biochemistry of foods or the analytical methods/ approach used. All papers should focus on the novelty of the research carried out.