Advanced optic-fiber sensor for progesterone concentration detection relying on the temperature-compensated reflective structure functionalized with molecularly imprinted polymer.

IF 6.5 1区农林科学 Q1 CHEMISTRY, APPLIED

Food Chemistry: X Pub Date : 2025-07-07 eCollection Date: 2025-07-01 DOI:10.1016/j.fochx.2025.102742

Hanlin Liu, Miao Liu, Shuyuan Guo, Jingru Mao, Yongfeng Zou, Yuejiang Yu, Dandan Sun, Jie Ma

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Abstract

A cascaded optic-reflector sensing system combining a microfiber interferometer (MFI) and a gold-coated tilted fiber Bragg grating (TFBG) is proposed for detecting progesterone (PG) concentration. The sensor uses molecularly imprinted polymers (MIP) as a recognition layer and metal-organic frameworks (MOFs) for enhanced sensitivity. The remove and rebind of PG will both cause changes in the local refractive index (RI) on MFI, and these changes can be monitored by the intensity variations on TFBG. Experimental results show a detection range of 10^-6-20 μg/ml, with a sensitivity of 41,837 dB/(μg/ml) and a limit of detection (LOD) of 10^-6 μg/ml. Simultaneously, it has been established that the sensor has good specificity in ten different real samples. This cascaded structure reflective sensor provides a simple and reliable technology for the quantitative detection of PG concentration in dairy products and water.

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基于分子印迹聚合物功能化的温度补偿反射结构的新型孕酮浓度检测光纤传感器。

提出了一种结合微光纤干涉仪（MFI）和镀金倾斜光纤布拉格光栅（TFBG）的级联光反射传感系统，用于检测孕酮（PG）浓度。该传感器使用分子印迹聚合物（MIP）作为识别层，使用金属有机框架（MOFs）提高灵敏度。PG的移除和再结合都会引起MFI上局部折射率（RI）的变化，这些变化可以通过TFBG上的强度变化来监测。实验结果表明，检测范围为10-6-20 μg/ml，灵敏度为41837 dB/(μg/ml)，检出限（LOD）为10-6 μg/ml。同时，该传感器在10种不同的实际样品中具有良好的特异性。该级联结构反射传感器为乳制品和水中PG浓度的定量检测提供了一种简单可靠的技术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Food Chemistry: X CHEMISTRY, APPLIED-

CiteScore

4.90

自引率

6.60%

发文量

315

审稿时长

55 days

期刊介绍： Food Chemistry: X, one of three Open Access companion journals to Food Chemistry, follows the same aims, scope, and peer-review process. It focuses on papers advancing food and biochemistry or analytical methods, prioritizing research novelty. Manuscript evaluation considers novelty, scientific rigor, field advancement, and reader interest. Excluded are studies on food molecular sciences or disease cure/prevention. Topics include food component chemistry, bioactives, processing effects, additives, contaminants, and analytical methods. The journal welcome Analytical Papers addressing food microbiology, sensory aspects, and more, emphasizing new methods with robust validation and applicability to diverse foods or regions.