{"title":"Advances in Protein and Polypeptide Drug Analytics.","authors":"Yuanli Mei, Hongmin Liu","doi":"10.2174/0113816128355706250626053659","DOIUrl":null,"url":null,"abstract":"<p><p>With the rapid advancement of biotechnology, protein and peptide drugs have become increasingly widespread in the medical field, yet their metabolic processes are complex and require the assistance of modern analytical methods for research. Based on the latest domestic and international research, this paper systematically reviews the application of modern analytical methods in the metabolism of protein and peptide drugs. The research focuses on key technologies such as biological activity detection, mass spectrometry, and chromatography, elaborating on their principles, characteristics, and current state of development. The aim is to provide scientific evidence and technical support for drug development, and to promote in-depth research on the metabolism of protein and peptide drugs.</p>","PeriodicalId":10845,"journal":{"name":"Current pharmaceutical design","volume":" ","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current pharmaceutical design","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2174/0113816128355706250626053659","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
Abstract
With the rapid advancement of biotechnology, protein and peptide drugs have become increasingly widespread in the medical field, yet their metabolic processes are complex and require the assistance of modern analytical methods for research. Based on the latest domestic and international research, this paper systematically reviews the application of modern analytical methods in the metabolism of protein and peptide drugs. The research focuses on key technologies such as biological activity detection, mass spectrometry, and chromatography, elaborating on their principles, characteristics, and current state of development. The aim is to provide scientific evidence and technical support for drug development, and to promote in-depth research on the metabolism of protein and peptide drugs.
期刊介绍：
Current Pharmaceutical Design publishes timely in-depth reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.
Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.
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