Design of a low-power gradient amplifier for benchtop nuclear magnetic resonance spectrometer

IF 2.3 4区医学 Q3 ENGINEERING, BIOMEDICAL

Medical Engineering & Physics Pub Date : 2025-07-12 DOI:10.1016/j.medengphy.2025.104395

Yuhao Gao , Tingwei Liu , Jinyu Yang , Ya Wang , Bowen Peng , Shihao Tang , Xiaodong Yang , Yajie Xu

引用次数: 0

Abstract

Benchtop Nuclear Magnetic Resonance (BNMR) technology has gained increasing attention in chemical and pharmaceutical applications due to its compact configuration and operational flexibility. However, the implementation of conventional commercial gradient amplifiers in BNMR systems remains challenging because of their excessive power consumption and bulky dimensions. To address these limitations, this study presents a novel gradient amplifier design optimized for BNMR applications, characterized by a satisfactory linearity in 0–2.5A output current range (slope: 0.9205, offset: 0.0359 and determination coefficient: 0.9963) and achieving a rise time of 1.41μs across dynamic output conditions (60 %, 80 %, 100 % amplitude range). Experimental validation confirms that these technical improvements satisfy the critical requirements for practical BNMR implementations.

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台式核磁共振光谱仪用低功率梯度放大器的设计

台式核磁共振（BNMR）技术由于其结构紧凑和操作灵活，在化学和制药应用中获得了越来越多的关注。然而，在BNMR系统中实现传统的商用梯度放大器仍然具有挑战性，因为它们的功耗过高且尺寸庞大。为了解决这些限制，本研究提出了一种针对BNMR应用优化的新型梯度放大器设计，其特点是在0-2.5A输出电流范围内（斜率：0.9205，偏置：0.0359，决定系数：0.9963）具有令人满意的线性度，并且在动态输出条件下（60%,80%，100%幅度范围）的上升时间为1.41μs。实验验证证实，这些技术改进满足了实际BNMR实现的关键要求。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Medical Engineering & Physics 工程技术-工程：生物医学

CiteScore

4.30

自引率

4.50%

发文量

172

审稿时长

3.0 months

期刊介绍： Medical Engineering & Physics provides a forum for the publication of the latest developments in biomedical engineering, and reflects the essential multidisciplinary nature of the subject. The journal publishes in-depth critical reviews, scientific papers and technical notes. Our focus encompasses the application of the basic principles of physics and engineering to the development of medical devices and technology, with the ultimate aim of producing improvements in the quality of health care.Topics covered include biomechanics, biomaterials, mechanobiology, rehabilitation engineering, biomedical signal processing and medical device development. Medical Engineering & Physics aims to keep both engineers and clinicians abreast of the latest applications of technology to health care.