{"title":"Bioactive compounds, health benefits, and practical applications of edible mushroom Schizophyllum commune Fr.: A decade-long critical review","authors":"Yogesh Kumar , Baojun Xu","doi":"10.1016/j.foodchem.2025.145583","DOIUrl":null,"url":null,"abstract":"<div><div><em>Schizophyllum commune</em>, also known as split-gill mushroom, is an edible fungus with significant medicinal and culinary value. This review explores the bioactive compounds, health benefits, and applications based on research from the last decade. Mushrooms like <em>S. commune</em> are rich in polysaccharides, flavonoids, saponins, and ergosterol, contributing to their antioxidant, antibacterial, antiviral, anti-inflammatory, and immunomodulatory properties. These compounds suggest potential in preventing and managing chronic diseases such as cancer, cardiovascular issues, diabetes, and neurodegenerative conditions. <em>S. commune</em> shows strong antioxidant activity, protecting cells from oxidative stress and DNA damage. It also demonstrates genoprotective and organoprotective effects, particularly against environmental toxins like Bisphenol A. Apart from medicinal use, <em>S. commune</em> acts have applications in pharmaceuticals, functional foods, and nutraceuticals, with notable antibacterial and anticancer effects. It is safe for consumption with no toxicity at high doses and it also offers potential in liver protection, metabolic disorders, and immune health.</div></div>","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"492 ","pages":"Article 145583"},"PeriodicalIF":9.8000,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food Chemistry","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0308814625028341","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
Schizophyllum commune, also known as split-gill mushroom, is an edible fungus with significant medicinal and culinary value. This review explores the bioactive compounds, health benefits, and applications based on research from the last decade. Mushrooms like S. commune are rich in polysaccharides, flavonoids, saponins, and ergosterol, contributing to their antioxidant, antibacterial, antiviral, anti-inflammatory, and immunomodulatory properties. These compounds suggest potential in preventing and managing chronic diseases such as cancer, cardiovascular issues, diabetes, and neurodegenerative conditions. S. commune shows strong antioxidant activity, protecting cells from oxidative stress and DNA damage. It also demonstrates genoprotective and organoprotective effects, particularly against environmental toxins like Bisphenol A. Apart from medicinal use, S. commune acts have applications in pharmaceuticals, functional foods, and nutraceuticals, with notable antibacterial and anticancer effects. It is safe for consumption with no toxicity at high doses and it also offers potential in liver protection, metabolic disorders, and immune health.
期刊介绍:
Food Chemistry publishes original research papers dealing with the advancement of the chemistry and biochemistry of foods or the analytical methods/ approach used. All papers should focus on the novelty of the research carried out.