The GNPC provides a proteomic resource for biomarker discovery and mechanistic insight in neurodegenerative disease

Abstract

The Global Neurodegeneration Proteomics Consortium (GNPC) is a multifaceted open-data resource of about 250 million protein measurements for biomarker discovery and mechanistic research across several neurodegenerative diseases. By harmonizing large-scale proteomic datasets with clinical data across 23 studies, the GNPC offers an important resource for neurodegenerative disease research and a template for large-scale data sharing in other scientific endeavors.