Safety and efficacy of a feed additive consisting of endo-1,4-beta-xylanase EC 3.2.1.8 produced by Bacillus subtilis LMG S-15136 (Belfeed B MP/ML) for gestating sows (Puratos NV)

IF 3.3 3区农林科学 Q2 FOOD SCIENCE & TECHNOLOGY

EFSA Journal Pub Date : 2025-07-16 DOI:10.2903/j.efsa.2025.9552

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López-Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto-Maradona, Ilen Röhe, Katerina Theodoridou, Vasileios Bampidis, Giovanna Martelli, Baltasar Mayo, Montserrat Anguita, Nicole Bozzi Cionci, Matteo L. Innocenti, Fabiola Pizzo, Jordi Ortuño

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Abstract

Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Belfeed B MP/ML as a feed additive for gestating sows when used at 10 IU/kg feed. The additive contains endo-1,4-b-xylanase produced by a genetically modified strain of Bacillus subtilis (LMG S-15136). The FEEDAP Panel concluded that the additive is safe for the target species at the proposed use level and that there are no concerns regarding the use of Belfeed B MP/ML for the consumers and for the environment. The two formulations of the additive were considered skin and eye irritants and respiratory sensitisers. The Panel concluded that the additive has the potential to be efficacious as a zootechnical additive in sows during the gestation period at 10 IU/kg feed.

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枯草芽孢杆菌LMG S-15136 （Belfeed B MP/ML）产内毒素-1,4- β -木聚糖酶EC 3.2.1.8饲料添加剂用于妊娠母猪（焙乐道）的安全性和有效性

应欧盟委员会的要求，动物饲料中使用的添加剂和产品或物质小组（FEEDAP）被要求就Belfeed B MP/ML作为妊娠母猪饲料添加剂在10 IU/kg饲料中使用的安全性和有效性发表科学意见。该添加剂含有一种转基因枯草芽孢杆菌菌株（LMG S-15136）产生的内切-1,4-b木聚糖酶。FEEDAP小组的结论是，在建议的使用水平下，该添加剂对目标物种是安全的，并且使用Belfeed B MP/ML对消费者和环境没有任何担忧。这两种添加剂的配方被认为是皮肤和眼睛刺激物，以及呼吸道致敏物。评估小组得出结论，该添加剂在妊娠期母猪中作为动物技术添加剂，在10 IU/kg饲料中具有潜在的有效性。

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来源期刊

EFSA Journal Veterinary-Veterinary (miscellaneous)

CiteScore

5.20

自引率

21.20%

发文量

422

审稿时长

5 weeks

期刊介绍： The EFSA Journal covers methods of risk assessment, reports on data collected, and risk assessments in the individual areas of plant health, plant protection products and their residues, genetically modified organisms, additives and products or substances used in animal feed, animal health and welfare, biological hazards including BSE/TSE, contaminants in the food chain, food contact materials, enzymes, flavourings and processing aids, food additives and nutrient sources added to food, dietetic products, nutrition and allergies.