A next generation probiotic, Bacteroides xylanisolvens

IF 15.1 1区农林科学 Q1 FOOD SCIENCE & TECHNOLOGY

Trends in Food Science & Technology Pub Date : 2025-07-11 DOI:10.1016/j.tifs.2025.105173

Chunhua Chen, Qixing Nie, Qiongni Lin, Jianqiao Zou, Shaoping Nie

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引用次数: 0

Abstract

Background

Since the discovery and characterization of Bacteroides xylanisolvens a decade ago, the probiotic effects of B. xylanisolvens, including immune regulation, metabolic modulation and maintenance of intestinal health, have been extensively investigated.

Scope and approach

This review summarizes the characterization and safety assessment of Bacteroides xylanisolvens, as well as the dietary and pharmaceutical determinants of its intestinal abundance. Additionally, it is also discussed that the bioactive metabolites produced by B. xylanisolvens and their associated mechanisms in improving host health and disease.

Key findings and conclusions

B. xylanisolvens is a microorganism with development potential. The European Commission has approved the use of B. xylanisolvens in pasteurized dairy products, which possesses extensive probiotic properties. The beneficial effects of B. xylanisolvens are closely related to γ-Aminobutyric acid, tryptophan metabolites, short-chain fatty acids, and folate production. These bioactive metabolites can protect the intestinal barrier, improve metabolic diseases, and regulate immune responses. Moreover, multiple studies indicates that B. xylanisolvens is related to the host's health and plays an important role in the improvement of diseases. Therefore, elucidating the interaction between B. xylanisolvens and the host will increase our understanding of its impact on human health and provide new insights for it to become the next-generation probiotic.

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下一代益生菌，溶木杆菌

自十年前发现并鉴定出溶木拟杆菌以来，人们对溶木拟杆菌的益生菌作用进行了广泛的研究，包括免疫调节、代谢调节和肠道健康的维持。本文综述了溶木胺拟杆菌的特性和安全性评价，以及其肠道丰度的饮食和药物决定因素。此外，本文还讨论了溶木杆菌产生的生物活性代谢物及其改善宿主健康和疾病的相关机制。主要发现和结论溶木聚糖菌是一种极具发展潜力的微生物。欧盟委员会已经批准在巴氏杀菌乳制品中使用木聚糖溶酵素，它具有广泛的益生菌特性。溶木芽孢杆菌的有益作用与γ-氨基丁酸、色氨酸代谢物、短链脂肪酸和叶酸的产生密切相关。这些生物活性代谢物可以保护肠道屏障，改善代谢性疾病，调节免疫反应。此外，多项研究表明，溶木芽胞杆菌与宿主健康有关，对疾病的改善有重要作用。因此，阐明溶木杆菌与宿主之间的相互作用将增加我们对其对人类健康影响的认识，并为其成为下一代益生菌提供新的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in Food Science & Technology 工程技术-食品科技

CiteScore

32.50

自引率

2.60%

发文量

322

审稿时长

37 days

期刊介绍： Trends in Food Science & Technology is a prestigious international journal that specializes in peer-reviewed articles covering the latest advancements in technology, food science, and human nutrition. It serves as a bridge between specialized primary journals and general trade magazines, providing readable and scientifically rigorous reviews and commentaries on current research developments and their potential applications in the food industry. Unlike traditional journals, Trends in Food Science & Technology does not publish original research papers. Instead, it focuses on critical and comprehensive reviews to offer valuable insights for professionals in the field. By bringing together cutting-edge research and industry applications, this journal plays a vital role in disseminating knowledge and facilitating advancements in the food science and technology sector.