Advancements in Nanotechnology for Autism Spectrum Disorder: Innovative Strategies in Pediatric Neurology

IF 2.7 4区医学 Q2 DEVELOPMENTAL BIOLOGY

Developmental Neurobiology Pub Date : 2025-07-07 DOI:10.1002/dneu.22989

Haozhen Li, Jing Zhang

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引用次数: 0

Abstract

Autism spectrum disorder (ASD) presents significant challenges in pediatric neurology, necessitating innovative management strategies to improve outcomes for affected children. This review explores the transformative potential of nanotechnology in autism treatment, highlighting specific applications of nanoscale materials and devices. We provide a detailed examination of various nanotechnology-based interventions, including targeted drug delivery systems that boost therapeutic efficacy, nanosensors for the early detection of ASD, and nanocarriers designed for gene therapy, all aimed at minimizing side effects while maximizing treatment benefits. Additionally, we discuss the role of nanotechnology in developing personalized medicine approaches tailored to the unique neurobiological profiles of children with ASD. By bridging the gap between research and clinical practice, this review aims to enhance the quality of care and life for pediatric patients with autism. We underscore the importance of interdisciplinary collaboration in advancing nanotechnology solutions and call for further research to validate these innovative strategies in pediatric neurology.

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纳米技术在自闭症谱系障碍中的进展：儿科神经病学的创新策略

自闭症谱系障碍（ASD）在儿童神经病学中提出了重大挑战，需要创新的管理策略来改善患儿的预后。这篇综述探讨了纳米技术在自闭症治疗中的变革潜力，重点介绍了纳米材料和器件的具体应用。我们提供了各种基于纳米技术的干预措施的详细检查，包括提高治疗效果的靶向药物输送系统，用于ASD早期检测的纳米传感器，以及用于基因治疗的纳米载体，所有这些都旨在最大限度地减少副作用，同时最大限度地提高治疗效益。此外，我们还讨论了纳米技术在开发针对自闭症儿童独特神经生物学特征的个性化医疗方法中的作用。通过弥合研究与临床实践之间的差距，本综述旨在提高儿童自闭症患者的护理质量和生活质量。我们强调跨学科合作在推进纳米技术解决方案方面的重要性，并呼吁进一步研究以验证这些创新的儿科神经病学策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Developmental Neurobiology 生物-发育生物学

CiteScore

6.50

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： Developmental Neurobiology (previously the Journal of Neurobiology ) publishes original research articles on development, regeneration, repair and plasticity of the nervous system and on the ontogeny of behavior. High quality contributions in these areas are solicited, with an emphasis on experimental as opposed to purely descriptive work. The Journal also will consider manuscripts reporting novel approaches and techniques for the study of the development of the nervous system as well as occasional special issues on topics of significant current interest. We welcome suggestions on possible topics from our readers.