{"title":"Electrospun Food Nanofibers for Hormonal Delivery: New Strategy in Sustainable Pharmaceutical Delivery System.","authors":"Deepak Kumar, Rishabha Malviya, Sathvik Belagodu Sridhar, Javedh Shareef, Tarun Wadhwa, Mullaicharam Bhupathyraaj, Musarrat Husain Warsi","doi":"10.2174/0113816128378108250612102634","DOIUrl":null,"url":null,"abstract":"<p><p>Electrospinning is an innovative process that produces polymeric fibres for a variety of purposes, including controlled hormone administration. These fibres are made from biopolymers like chitosan, cellulose, alginate, and starch, and have attracted interest for their capacity to encapsulate hormones and release them in a regulated way, therefore Increasing bioavailability and stability. The article investigates the utilization of smart electrospun fibers for hormone delivery, alongside a focus on their potential to improve therapeutic results. Electrospun fibres can encapsulate hormones such as insulin, melatonin, and contraceptives for regulated and prolonged release. This method addresses difficulties in traditional hormone delivery, like frequent insulin injections or hormone instability in biological circumstances. Techniques like coaxial electrospinning enable the development of core-shell structures, which further optimize release profiles. The use of these fibres for diabetic management, wound healing, and long-term contraception represents substantial advances in patient care. The flexibility of fibres also allows for precise regulation of drug release kinetics, which improves the efficacy of hormone therapy while reducing adverse effects. Smart electrospun food fibres have enormous promise for the future of hormone administration, providing longer-lasting, more focused, and effective therapies. Their flexibility, along with ongoing advances in electrospinning processes, positions them as a viable tool in contemporary medicine.</p>","PeriodicalId":10845,"journal":{"name":"Current pharmaceutical design","volume":" ","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current pharmaceutical design","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2174/0113816128378108250612102634","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
Abstract
Electrospinning is an innovative process that produces polymeric fibres for a variety of purposes, including controlled hormone administration. These fibres are made from biopolymers like chitosan, cellulose, alginate, and starch, and have attracted interest for their capacity to encapsulate hormones and release them in a regulated way, therefore Increasing bioavailability and stability. The article investigates the utilization of smart electrospun fibers for hormone delivery, alongside a focus on their potential to improve therapeutic results. Electrospun fibres can encapsulate hormones such as insulin, melatonin, and contraceptives for regulated and prolonged release. This method addresses difficulties in traditional hormone delivery, like frequent insulin injections or hormone instability in biological circumstances. Techniques like coaxial electrospinning enable the development of core-shell structures, which further optimize release profiles. The use of these fibres for diabetic management, wound healing, and long-term contraception represents substantial advances in patient care. The flexibility of fibres also allows for precise regulation of drug release kinetics, which improves the efficacy of hormone therapy while reducing adverse effects. Smart electrospun food fibres have enormous promise for the future of hormone administration, providing longer-lasting, more focused, and effective therapies. Their flexibility, along with ongoing advances in electrospinning processes, positions them as a viable tool in contemporary medicine.
期刊介绍:
Current Pharmaceutical Design publishes timely in-depth reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.
Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.