[Alcohol use disorder: screening, diagnosis and follow-up].

Q3 Pharmacology, Toxicology and Pharmaceutics
Neuropsychopharmacologia Hungarica Pub Date : 2025-06-01
Otilia Bagi, Fanni Fruzsina Farkas, Janka Gajdics, Ildiko Katalin Pribek, Bence Andras Lazar
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引用次数: 0

Abstract

Aims: In the clinical assessment of alcohol use disorder (AUD), measuring tools are essential to help recognizing the condition, determining the severity of the disorder, and assessing craving and relapse after identifying potential complications. Currently, there are no measurement tools available in Hungary that can quantify the severity of alcohol dependence, the extent of alcohol craving, and the risk of relapse, or help in the early detection of complicated alcohol withdrawal syndrome (c-AWS). There for the aim of the present study was to evaluate the psychometric indicators of the Hungarian versions of the Severity of Alcohol Dependence Questionnaire (SAD-Q), Penn Alcohol Craving Scale (PACS), Multidimensional Alcohol Craving Scale (MACS), Alcohol Relapse Risk Scale (ARRS), and the Prediction of Alcohol Withdrawal Severity Scale (PAWSS).

Methods: The present study was conducted among patients (n = 44) admitted to the Department of Psychiatry, University of Szeged with a diagnosis of alcohol dependence, alcohol withdrawal syndrome, or alcohol withdrawal syndrome with delirium. In addition to the aforementioned questionnaires, the Alcohol Use Disorders Identification Test (AUDIT) and Visual Analogue Scale (VAS) were administered. Internal consistency coefficients (Cronbach's alpha, item-total correlation) and convergent validity indices (Spearman correlations) were calculated, Mann-Whitney test was used to assess differences in the risk of relapse for the ARRS total score, and the independent-sample t-test was used to explore differences in complicated and non- complicated withdrawal for the PAWSS total score. In addition, binomial logistic regression was performed for both scales to analyze whether total scores were good predictors of c-AWS and relapse.

Results: Cronbach's alpha values ranged from 0.875 to 0.948, and the construct validity indices (Spearman correlations) ranged from 0.537 to 0.760. For the ARRS, significantly higher total scores were found for those who relapsed within 3 months, and for the PAWSS, significantly higher total scores were found for patients experiencing complicated withdrawal. The ARRS and PAWSS total scores are good predictors of relapse and c-AWS.

Conclusions: Based on our results, the questionnaires listed are reliable and valid measuring instruments, and their use might facilitate a more modern investigation and treatment of AUD.

[酒精使用障碍:筛查、诊断和随访]。
目的:在酒精使用障碍(AUD)的临床评估中,测量工具对于帮助识别病情,确定障碍的严重程度以及在识别潜在并发症后评估渴望和复发是必不可少的。目前,匈牙利没有测量工具可以量化酒精依赖的严重程度、渴望酒精的程度和复发的风险,也没有工具可以帮助早期发现复杂的酒精戒断综合征(c-AWS)。本研究的目的是评估匈牙利版酒精依赖严重程度问卷(SAD-Q)、宾州酒精渴望量表(PACS)、多维酒精渴望量表(MACS)、酒精复发风险量表(ARRS)和酒精戒断严重程度预测量表(PAWSS)的心理测量指标。方法:本研究纳入了塞格德大学精神科诊断为酒精依赖、酒精戒断综合征或酒精戒断综合征伴谵妄的患者(n = 44)。除上述问卷外,还进行了酒精使用障碍识别测试(AUDIT)和视觉模拟量表(VAS)。计算内部一致性系数(Cronbach's alpha,项目-总相关)和收敛效度指数(Spearman相关),采用Mann-Whitney检验评估ARRS总分复发风险的差异,采用独立样本t检验探讨PAWSS总分复杂和非复杂戒断的差异。此外,对两种量表进行二项逻辑回归,以分析总分是否是c-AWS和复发的良好预测因子。结果:Cronbach’s alpha值为0.875 ~ 0.948,构效度指数(Spearman相关)为0.537 ~ 0.760。在ARRS中,3个月内复发的患者总得分明显较高,而在PAWSS中,出现复杂戒断的患者总得分明显较高。ARRS和PAWSS总分是预测复发和c-AWS的良好指标。结论:根据我们的研究结果,所列出的问卷是可靠和有效的测量工具,它们的使用可能有助于更现代的AUD调查和治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Neuropsychopharmacologia Hungarica
Neuropsychopharmacologia Hungarica Medicine-Medicine (all)
CiteScore
1.60
自引率
0.00%
发文量
8
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