Detection of Toxoplasma Gondii Tachyzoites in Cerebrospinal Fluid: Once in a Blue Moon Finding

IF 1.1 4区医学 Q4 CELL BIOLOGY

Cytopathology Pub Date : 2025-06-23 DOI:10.1111/cyt.70005

Ananthanarayanan Udupi Suryanarayana, Vidhya Vikashini Balasubramaniam, Kalisetty Prashanthi, Debasis Gochhait, Hariswar Pari

引用次数: 0

Abstract

Detection of tachyzoites of Toxoplasma gondii in cerebrospinal fluid led to the diagnosis of central nervous system (CNS) toxoplasmosis in a 20 years old male. The cerebrospinal fluid (CSF) was obtained by lumbar puncture and two cytology smears were prepared by cytocentrifugation, one of which was stained with the May-Grünwald Giemsa (MGG) stain and the other with Papanicolaou stain. Light microscopic examination revealed pleocytosis along with numerous intracellular phagocytosed as well as extracellular tachyzoites with cytomorphology characteristic of Toxoplasma gondii. The diagnosis was confirmed by the serological elevation of anti-Toxoplasma IgM levels.

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脑脊液中刚地弓形虫速殖子的检测：千载难逢的发现。

1例20岁男性脑脊液中检测弓形虫速殖子，诊断为中枢神经系统弓形虫病。腰椎穿刺取脑脊液（CSF），细胞离心涂片2张，分别用may - gr nwald Giemsa （MGG）染色和Papanicolaou染色。光镜检查显示多细胞增生，细胞内大量吞噬和细胞外速殖子，具有刚地弓形虫的细胞形态学特征。血清抗弓形虫IgM水平升高证实了诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cytopathology 生物-病理学

CiteScore

2.30

自引率

15.40%

发文量

107

审稿时长

6-12 weeks

期刊介绍： The aim of Cytopathology is to publish articles relating to those aspects of cytology which will increase our knowledge and understanding of the aetiology, diagnosis and management of human disease. It contains original articles and critical reviews on all aspects of clinical cytology in its broadest sense, including: gynaecological and non-gynaecological cytology; fine needle aspiration and screening strategy. Cytopathology welcomes papers and articles on: ultrastructural, histochemical and immunocytochemical studies of the cell; quantitative cytology and DNA hybridization as applied to cytological material.