Efficacy of a feed additive consisting of endo-1,4-beta-xylanase, endo-1,4-beta-glucanase and xyloglucan-specific-endo-beta-1,4-glucanase produced by Trichoderma citrinoviride DSM 33578 (Huvezym® neXo) for all porcine species and all poultry (Huvepharma EOOD)

IF 3.3 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López-Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto-Maradona, Ilen Röhe, Katerina Theodoridou, Noël Dierick, Montserrat Anguita, Matteo L. Innocenti, Marianna Kujawa, Jordi Ortuño
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引用次数: 0

Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the efficacy of endo-1,4-beta-xylanase, endo-1,4-beta-glucanase and xyloglucan-specific-endo-beta-1,4-glucanase (produced with Trichoderma citrinoviride DSM 33578) (Huvezym® neXo), intended to be used as a zootechnical feed additive (functional group: digestibility enhancers) for all Suidae and all poultry at the recommended application level 1500 endo-pentosanase units (EPU), 100 cellulase unit (CU) and 100 xyloglucanase unit (XGU)/kg of complete feed. The additive is available in granulated (Huvezym® neXo 100 G) and liquid (Huvezym® neXo100 L) forms, and it is authorised for use in reproductive sows and poultry for fattening, poultry reared for laying and reared for breeding, and ornamental birds. In previous opinions, the FEEDAP Panel concluded that Huvezym® neXo is safe for the target species, consumers and the environment. Additionally, the FEEDAP Panel concluded that Huvezym® neXo in either form is not an irritant to the skin and eyes; the liquid form is not a skin sensitiser, but the solid form should be considered a potential skin sensitiser. Both forms of the additive are considered respiratory sensitisers. However, in the previous assessments, the Panel could not conclude on the efficacy of weaned piglets and laying hens. Considering the previously and newly submitted data the Panel concluded that the additive has a potential to be efficacious as a zootechnical additive for all porcine species and all poultry under the proposed conditions of use.

由黄绿木霉DSM 33578 (Huvezym®neXo)生产的内切-1,4- β -葡聚糖酶、内切-1,4- β -葡聚糖酶和木葡聚糖特异性内切- β -1,4-葡聚糖酶组成的饲料添加剂对所有猪种和所有家禽的功效(Huvepharma EOOD)
根据欧盟委员会的要求,欧洲食品安全局被要求对拟作为动物技术饲料添加剂的内切-1,4- β -木聚糖酶、内切-1,4- β -葡聚糖酶和木聚糖特异性内切- β -1,4-葡聚糖酶(用柠檬酸木霉DSM 33578生产)(Huvezym®neXo)的功效发表科学意见。消化率增强剂),推荐添加水平为1500内戊聚糖酶单位(EPU)、100纤维素酶单位(CU)和100木葡聚糖酶单位(XGU)/kg全饲料。该添加剂有颗粒状(Huvezym®neXo100 G)和液体状(Huvezym®neXo100 L)两种形式,被授权用于繁殖母猪和家禽的育肥,用于产蛋和饲养的家禽,以及观赏鸟类。在之前的意见中,FEEDAP小组得出结论,Huvezym®neXo对目标物种、消费者和环境是安全的。此外,FEEDAP小组得出结论,两种形式的Huvezym®neXo都不会对皮肤和眼睛产生刺激;液体形式不是皮肤致敏剂,但固体形式应被认为是潜在的皮肤致敏剂。这两种添加剂都被认为是呼吸道致敏剂。然而,在之前的评估中,专家小组未能就断奶仔猪和蛋鸡的功效得出结论。考虑到以前和新提交的数据,小组得出结论认为,在拟议的使用条件下,该添加剂有可能作为动物技术添加剂对所有猪种和所有家禽有效。
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来源期刊
EFSA Journal
EFSA Journal Veterinary-Veterinary (miscellaneous)
CiteScore
5.20
自引率
21.20%
发文量
422
审稿时长
5 weeks
期刊介绍: The EFSA Journal covers methods of risk assessment, reports on data collected, and risk assessments in the individual areas of plant health, plant protection products and their residues, genetically modified organisms, additives and products or substances used in animal feed, animal health and welfare, biological hazards including BSE/TSE, contaminants in the food chain, food contact materials, enzymes, flavourings and processing aids, food additives and nutrient sources added to food, dietetic products, nutrition and allergies.
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