{"title":"CoCliP-BJI study: cost avoidance of clinical pharmacist-led interventions in patients with bone and joint infections","authors":"Eloïse Couvé , Marin Lahouati , Julie Leitao , Vasco Dias Meireles , Fréderic-Antoine Dauchy , Fabien Xuereb","doi":"10.1016/j.idnow.2025.105104","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><div>Patients with bone and joint infections (BJI) are part of a complex care pathway. This study aimed to evaluate the economic impact of clinical pharmacist-led interventions in the management of BJI patients.</div></div><div><h3>Patients and Methods</h3><div>We performed a retrospective study documenting all pharmacist-led interventions (PI). Their impact was assessed using the clinical economic and organizational scale (CLEO SFPC). The probability of adverse drug events (ADE) in the absence of PI was assessed by a panel of three experts. Cost avoidance was calculated for PIs with major clinical impact using a cost of €5,331 per event, multiplied by the probability of ADE occurrence.</div></div><div><h3>Results</h3><div>A total of 41 PIs had a major clinical impact. Cost avoidance associated with the intervention of a pharmacist was estimated at €83,750.01 during the study.</div></div><div><h3>Conclusion</h3><div>The implementation of pharmacist-led interventions in the management of patients with BJI helps avoid preventable healthcare costs.</div></div>","PeriodicalId":13539,"journal":{"name":"Infectious diseases now","volume":"55 6","pages":"Article 105104"},"PeriodicalIF":2.9000,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infectious diseases now","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666991925000831","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0
Abstract
Objectives
Patients with bone and joint infections (BJI) are part of a complex care pathway. This study aimed to evaluate the economic impact of clinical pharmacist-led interventions in the management of BJI patients.
Patients and Methods
We performed a retrospective study documenting all pharmacist-led interventions (PI). Their impact was assessed using the clinical economic and organizational scale (CLEO SFPC). The probability of adverse drug events (ADE) in the absence of PI was assessed by a panel of three experts. Cost avoidance was calculated for PIs with major clinical impact using a cost of €5,331 per event, multiplied by the probability of ADE occurrence.
Results
A total of 41 PIs had a major clinical impact. Cost avoidance associated with the intervention of a pharmacist was estimated at €83,750.01 during the study.
Conclusion
The implementation of pharmacist-led interventions in the management of patients with BJI helps avoid preventable healthcare costs.