{"title":"Comment on “Differential Diagnosis of Urinary Cancers by Surface-Enhanced Raman Spectroscopy and Machine Learning”","authors":"Ivan A. Bratchenko, Lyudmila A. Bratchenko","doi":"10.1021/acs.analchem.5c00517","DOIUrl":null,"url":null,"abstract":"This article discusses current research on the detection of urinary cancers using surface-enhanced Raman spectral analysis of human serum by Song et al., which was published in the Analytical Chemistry journal. Despite the high performance of the suggested approach (ROC AUC of 0.94), the demonstrated performance could be treated as overoptimistic because of an overestimation of classification models.","PeriodicalId":27,"journal":{"name":"Analytical Chemistry","volume":"5 1","pages":""},"PeriodicalIF":6.7000,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analytical Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1021/acs.analchem.5c00517","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
This article discusses current research on the detection of urinary cancers using surface-enhanced Raman spectral analysis of human serum by Song et al., which was published in the Analytical Chemistry journal. Despite the high performance of the suggested approach (ROC AUC of 0.94), the demonstrated performance could be treated as overoptimistic because of an overestimation of classification models.
期刊介绍:
Analytical Chemistry, a peer-reviewed research journal, focuses on disseminating new and original knowledge across all branches of analytical chemistry. Fundamental articles may explore general principles of chemical measurement science and need not directly address existing or potential analytical methodology. They can be entirely theoretical or report experimental results. Contributions may cover various phases of analytical operations, including sampling, bioanalysis, electrochemistry, mass spectrometry, microscale and nanoscale systems, environmental analysis, separations, spectroscopy, chemical reactions and selectivity, instrumentation, imaging, surface analysis, and data processing. Papers discussing known analytical methods should present a significant, original application of the method, a notable improvement, or results on an important analyte.