Exploring Treatment Adherence in Children Aged 0-6 With Atopic Dermatitis: A Pilot Cross-Sectional Study in China.

IF 1.2 4区医学 Q3 DERMATOLOGY

Pediatric Dermatology Pub Date : 2025-05-28 DOI:10.1111/pde.15968

Zizhuo Li, Xinming Mai, Yan Liao, Heng Yang, Chener Yang, Jiaying Chen, Lu Wei, Xia Dou, Chengxin Li

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引用次数: 0

Abstract

Background/objectives: Atopic dermatitis (AD) is a common chronic inflammatory skin disease in pediatric populations, yet treatment adherence remains a persistent challenge. This study aims to assess caregivers' perceptions of treatment and investigate the factors influencing treatment adherence in children with AD in China.

Methods: A cross-sectional study was conducted at the Department of Dermatology, Peking University Shenzhen Hospital, between April and December 2023. Demographic and disease information were collected. Caregivers were assessed using the Topical Corticosteroid Phobia (TOPICOP) questionnaire, the Treatment Satisfaction Questionnaire for Medication-9 (TSQM-9), and the 8-item Morisky Medication Adherence Scale (MMAS-8).

Results: A total of 100 children were enrolled, most with mild-to-moderate disease severity. 88% of patients reported using topical corticosteroids. The median caregiver global TOPICOP score was 55.6% (IQR 41.7%-67.4%) with a standard deviation (SD) of 17.2%. The mean MMAS score was 4.48 (SD 1.42), and the median was 4.75 (IQR 3.50-6.00). Overall, adherence was generally low, with 72% of caregivers demonstrating low adherence, 23% demonstrating medium adherence, and 4% demonstrating high adherence. Caregivers of male children and male caregivers showed significantly higher adherence. Lower caregiver ratings of treatment convenience were associated with poorer adherence, whereas caregiver education level and corticophobia were not associated with adherence.

Conclusions: The current treatment approach for children with eczema in China was generally poor, and treatment convenience was an important factor influencing caregiver adherence.

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探索0-6岁特应性皮炎儿童的治疗依从性：中国的一项试点横断面研究。

背景/目的：特应性皮炎（AD）是儿科人群中一种常见的慢性炎症性皮肤病，但治疗依从性仍然是一个持续的挑战。本研究旨在评估照顾者对治疗的认知，并探讨影响中国AD患儿治疗依从性的因素。方法：于2023年4月- 12月在北京大学深圳医院皮肤科进行横断面研究。收集了人口统计和疾病信息。采用外用皮质类固醇恐惧量表（TOPICOP）、药物治疗满意度问卷（TSQM-9）和莫里斯基药物依从性量表（MMAS-8）对护理人员进行评估。结果：共纳入100名儿童，大多数为轻至中度疾病严重程度。88%的患者报告使用局部皮质类固醇。护理人员TOPICOP评分中位数为55.6% (IQR为41.7%-67.4%)，标准差（SD）为17.2%。平均MMAS评分为4.48 (SD 1.42)，中位数为4.75 （IQR 3.50-6.00）。总体而言，依从性普遍较低，72%的护理人员表现为低依从性，23%表现为中等依从性，4%表现为高依从性。男童照顾者和男童照顾者的依从性显著高于男童照顾者。较低的护理人员对治疗便利性的评分与较差的依从性相关，而护理人员的教育水平和皮质恐惧症与依从性无关。结论：目前中国儿童湿疹的治疗方法普遍较差，治疗便捷性是影响护理人员依从性的重要因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric Dermatology 医学-皮肤病学

CiteScore

3.20

自引率

6.70%

发文量

269

审稿时长

1 months

期刊介绍： Pediatric Dermatology answers the need for new ideas and strategies for today''s pediatrician or dermatologist. As a teaching vehicle, the Journal is still unsurpassed and it will continue to present the latest on topics such as hemangiomas, atopic dermatitis, rare and unusual presentations of childhood diseases, neonatal medicine, and therapeutic advances. As important progress is made in any area involving infants and children, Pediatric Dermatology is there to publish the findings.