Wang Lu, Rui Tang, Xiong Jiahui, Zhang Shipeng, Guo Tao, Wang Hanyua, Xiong Feng, Xie Hui
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引用次数: 0
Abstract
Background: Hearing loss ranks as the third most prevalent disability globally, significantly impacting individuals and society, and imposing a substantial healthcare burden. The World Health Organization reports that over 1.5 billion people worldwide experience hearing loss, with one-third of these cases attributed to preventable factors. Recently, the influence of diet and nutrition on auditory health has garnered increasing attention.
Objective: This study systematically reviews and meta-analyzes the protective effects of dietary nutrients on hearing, examining specific nutrients' impact on hearing loss and their potential biological mechanisms.
Methods: A comprehensive search of PubMed, Embase, Web of Science, and the Cochrane Library was conducted for relevant studies up to August 2024. Following PRISMA guidelines, the systematic review was registered in PROSPERO. Included were observational studies assessing the relationship between dietary intake and hearing loss.
Results: Thirty-three studies met inclusion criteria: 21 cross-sectional, 10 cohort, and 2 case-control studies. Meta-analysis revealed significant inverse associations between the intake of vitamin B2, β-carotene, carotenoids, β-cryptoxanthin, fat, protein, fiber, and fish, and the risk of hearing loss.
Conclusion: Certain dietary nutrients may protect hearing health. Increasing intake of antioxidants, fiber, protein, and fish rich in unsaturated fatty acids may help preserve auditory function.Keywords: Hearing loss, dietary nutrients, systematic review, meta-analysis, antioxidants.
背景：听力损失是全球第三大最普遍的残疾，对个人和社会产生重大影响，并造成巨大的医疗负担。世界卫生组织报告说，全世界有超过15亿人患有听力损失，其中三分之一的病例可归因于可预防的因素。近年来，饮食和营养对听觉健康的影响越来越受到人们的关注。目的：本研究系统回顾和荟萃分析了膳食营养素对听力的保护作用，探讨了特定营养素对听力损失的影响及其潜在的生物学机制。方法：综合检索PubMed、Embase、Web of Science、Cochrane Library，检索截止到2024年8月的相关研究。按照PRISMA的指导方针，系统评价在PROSPERO上注册。其中包括评估饮食摄入与听力损失之间关系的观察性研究。结果：33项研究符合纳入标准：21项横断面研究，10项队列研究，2项病例对照研究。荟萃分析显示，维生素B2、β-胡萝卜素、类胡萝卜素、β-隐黄质、脂肪、蛋白质、纤维和鱼类的摄入量与听力损失的风险呈显著负相关。结论：某些膳食营养素可保护听力健康。增加抗氧化剂、纤维、蛋白质和富含不饱和脂肪酸的鱼类的摄入可能有助于保持听觉功能。关键词：听力损失，膳食营养素，系统评价，荟萃分析，抗氧化剂系统综述注册：https://www.crd.york.ac.uk/PROSPERO/view/CRD42024572118，标识符：CRD42024572118。
期刊介绍：
No subject pertains more to human life than nutrition. The aim of Frontiers in Nutrition is to integrate major scientific disciplines in this vast field in order to address the most relevant and pertinent questions and developments. Our ambition is to create an integrated podium based on original research, clinical trials, and contemporary reviews to build a reputable knowledge forum in the domains of human health, dietary behaviors, agronomy & 21st century food science. Through the recognized open-access Frontiers platform we welcome manuscripts to our dedicated sections relating to different areas in the field of nutrition with a focus on human health.
Specialty sections in Frontiers in Nutrition include, for example, Clinical Nutrition, Nutrition & Sustainable Diets, Nutrition and Food Science Technology, Nutrition Methodology, Sport & Exercise Nutrition, Food Chemistry, and Nutritional Immunology. Based on the publication of rigorous scientific research, we thrive to achieve a visible impact on the global nutrition agenda addressing the grand challenges of our time, including obesity, malnutrition, hunger, food waste, sustainability and consumer health.
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